Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.44 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218864 | 0.81 | FAAH (0.61) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL28705775 | 0.78 | LPAR3 (0.49) | FAAHMEN1MAPK1KMT2AALDH1A1 | |
| SCHEMBL12460086 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL12540859 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL2058975 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL2058428 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL2058779 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| SCHEMBL2058989 | 0.78 | FAAH (0.71) | FAAHMEN1MAPK1KMT2ADNM1 | |
| Sulfuric Acid SCHEMBL31710486 | 0.78 | MEN1 (0.61) | FAAHMEN1MAPK1KMT2ADNM1 | |
| Sulfuric Acid SCHEMBL31710135 | 0.78 | MEN1 (0.61) | FAAHMEN1MAPK1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118973539-A | Process for preparing shelf stable sulfur-containing personal care compositions | 宝洁公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-115484920-B | Compositions with non-ethoxylated surfactants and co-surfactants to achieve good product consistency and performance | 宝洁公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-114423405-B | Personal care compositions comprising anti-dandruff agents | 宝洁公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114845694-B | Transparent composition with soluble scalp health active | 宝洁公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117015366-A | Method for enhancing deposition of scalp active material | 宝洁公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116761583-A | Efficacy of azoxystrobin in scalp health | 宝洁公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-116546965-A | Excellent efficacy of azoxystrobin and other strobilurins | 宝洁公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116322631-A | Low surfactant cosmetic composition comprising cationic polymer | 宝洁公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115996700-A | Efficacy of azoxystrobin in personal care forms | 宝洁公司 | 2023-04-21 | — | — | CN | disclosed |