Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 9/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017389 | 0.83 | OPRM1 (0.32) | OPRM1 | |
| SCHEMBL29017367 | 0.78 | OPRM1 (0.50) | OPRM1ALDH1A1GAAKMT2AMAOA | |
| SCHEMBL29017397 | 0.76 | ICMT (0.40) | ICMTHTTOPRM1MAOAMAOB | |
| SCHEMBL29017373 | 0.76 | SIGMAR1 (0.41) | ICMTOPRM1ALDH1A1 | |
| SCHEMBL29017415 | 0.74 | ICMT (0.63) | ICMT | |
| SCHEMBL5031526 | 0.73 | MAOA (0.41) | ICMTOPRM1MAOAMAOBTAAR1 | |
| SCHEMBL5480204 | 0.70 | HTT (0.37) | ADRB2ADRB1LMNAHTTKDM4E | |
| SCHEMBL29017417 | 0.70 | OPRM1 (0.63) | OPRM1KDM4EALDH1A1KMT2A | |
| SCHEMBL29017382 | 0.70 | HTR1A (0.61) | ICMTHTTOPRM1ALDH1A1KMT2A | |
| SCHEMBL29017405 | 0.70 | MAOB (0.50) | OPRM1KDM4EMAOAMAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116240194-B | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2024-11-12 | — | — | CN | disclosed |
| CN-116240194-A | Limonene epoxy hydrolase mutant and catalytic synthesis of chiral oxygen/nitrogen-heterocyclic compound thereof | 中国科学院天津工业生物技术研究所 | 2023-06-09 | — | — | CN | disclosed |