Potassium Ion

Potassium Ion

SCHEMBL29020100

O=C([O-])CCc1ccncc1.[K+]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.47
LMNA P02545 1/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.45
NPY5R Q15761 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium Ion SCHEMBL28456336 0.96 FFAR1 (0.47) FFAR1LMNAHDAC2HDAC8HDAC6
Potassium Ion SCHEMBL17653817 0.80 CYP19A1 (0.48) HDAC6HDAC1LOXL2ALDH1A1SMN1; SMN2
SCHEMBL6573723 0.80 FFAR1 (0.52) FFAR1LMNAHDAC2HDAC8HDAC6
SCHEMBL17142341 0.80 HDAC1 (0.59) FFAR1HDAC2HDAC8HDAC6HDAC3
Phenyl Propionic Acid SCHEMBL5351527 0.78 HDAC1 (0.70) FFAR1HDAC2HDAC8HDAC6HDAC3
SCHEMBL333186 0.78 FFAR1 (0.70) FFAR1LMNANPY5RTDP1ALDH1A1
Potassium Ion SCHEMBL27486991 0.77 TBXAS1 (0.58) TDP1NAMPT
SCHEMBL4662980 0.77 FFAR1 (0.49) FFAR1LMNAHDAC2HDAC8HDAC6
SCHEMBL660683 0.77 LOXL2 (0.52) FFAR1LMNAHDAC2HDAC8HDAC6
SCHEMBL1677975 0.77 ALDH1A1 (0.63) FFAR1LMNAHDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283897-A Compound and application of compound in solar cell 西安隆基乐叶光伏科技有限公司 2023-06-23 CN disclosed