Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2897637 | 0.85 | LMNA (0.39) | SMN1; SMN2LMNAHTTHPGDALDH1A1 | |
| SCHEMBL2897638 | 0.82 | CYP2C9 (0.49) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL6629345 | 0.79 | PIN1 (0.43) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL2902878 | 0.77 | LMNA (0.40) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL2901895 | 0.74 | HSPB1 (0.44) | SMN1; SMN2LMNAHTTRAB9AALDH1A1 | |
| SCHEMBL25340189 | 0.72 | KCNH2 (0.41) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL30482536 | 0.72 | KCNH2 (0.41) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL19086918 | 0.72 | ALDH1A1 (0.32) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11360493 | 0.71 | SMN1; SMN2 (0.71) | SMN1; SMN2LMNAHTTHPGDRAB9A | |
| SCHEMBL2894791 | 0.70 | MAPT (0.43) | LMNARAB9AMAPTNPSR1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | SMN1; SMN2 2519/4885LMNA 2262/4885HTT 2101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.