Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 5/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2910190 | 0.89 | GPR27 (0.42) | MEN1KMT2A | |
| SCHEMBL2908073 | 0.89 | NR1H4 (0.47) | L3MBTL1ITGA4CNR1CNR2MEN1 | |
| SCHEMBL2913446 | 0.88 | ALDH1A1 (0.36) | ALDH1A1BCL2LMNACFTRL3MBTL1 | |
| SCHEMBL2913166 | 0.88 | XDH (0.38) | ALDH1A1LMNACFTRL3MBTL1ITGA4 | |
| SCHEMBL2910683 | 0.85 | ALDH1A1 (0.36) | ALDH1A1LMNACFTRL3MBTL1ITGA4 | |
| SCHEMBL2910291 | 0.85 | CNR2 (0.38) | ALDH1A1LMNACFTRCNR2BCL2L1 | |
| SCHEMBL2910962 | 0.84 | RAB9A (0.39) | ALDH1A1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL2913556 | 0.84 | NPC1 (0.46) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL2913996 | 0.84 | CA1 (0.43) | ALDH1A1LMNACFTRMEN1KMT2A | |
| SCHEMBL2906969 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAL3MBTL1ITGA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |