SCHEMBL2908261

SCHEMBL2908261

N#CCC(=O)OCC1CO1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
MGLL Q99685 4/20 0.43
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14168784 0.87 LMNA (0.43) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL11239739 0.82 LMNA (0.66) ALDH1A1MGLLLMNAPOLB
SCHEMBL12284997 0.81 LMNA (0.59) ALDH1A1MGLLLMNAPOLB
SCHEMBL14168893 0.80 LMNA (0.36) ALDH1A1LMNAPOLB
SCHEMBL14169000 0.79 L3MBTL1 (0.36) ALDH1A1MGLLLMNAPOLB
SCHEMBL29678737 0.78 ALDH1A1 (0.50) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL2031900 0.77 CA2 (0.47) ALDH1A1LMNAPOLB
SCHEMBL1700804 0.77 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL471906 0.77 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL18938837 0.76 LMNA (0.43) ALDH1A1CYP3A4LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558936-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFIN PRECURSORS HENKEL AG & CO KGAA (DE) 2024-08-14 EP disclosed
EP-3558935-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS HENKEL AG & CO KGAA (DE) 2023-11-29 EP disclosed
CN-110114337-B Method for preparing electron-deficient olefins 汉高股份有限及两合公司 2023-05-30 CN disclosed
US-11639330-B2 Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium SHOWA DENKO K.K. (JP) 2023-05-02 US disclosed
CN-110121494-B Method for producing cyanoacrylic esters 汉高股份有限及两合公司 2023-02-17 CN disclosed
EP-3558933-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFIN PRECURSORS HENKEL AG & CO KGAA (DE) 2022-11-23 EP disclosed
EP-3558937-B1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS Henkel IP & Holding GmbH (DE) 2022-05-11 EP disclosed
US-10913707-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-02-09 US disclosed
US-10913708-B2 Process for preparing electron deficient olefin precursors Henkel IP & Holding GmbH (DE) 2021-02-09 US disclosed
US-10889542-B2 Process for preparing electron deficient olefins Henkel IP & Holding GmbH (DE) 2021-01-12 US disclosed
WO-2018114460-A1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS Henkel IP & Holding GmbH (DE) 2018-06-28 WO disclosed
WO-2018114464-A1 PROCESS FOR PREPARING ELECTRON DEFICIENT OLEFINS Henkel IP & Holding GmbH (DE) 2018-06-28 WO disclosed
EP-2217557-B1 ACTIVATED METHYLENE REAGENTS Henkel IP & Holding GmbH (DE) 2018-01-24 EP disclosed
CN-101896454-B Activated methylene reagents and curable compositions prepared therefrom LOCTITE R & D LTD 2013-07-10 CN disclosed
US-8481755-B2 Activated methylene reagents and curable compositions prepared therefrom HENKEL IRELAND LTD. (DE) 2013-07-09 US disclosed
US-8399698-B1 Substituted activated methylene reagents and methods of using such reagents to form electron deficient olefins HENKEL IRELAND LIMITED (DE) 2013-03-19 US disclosed
CN-101896454-A Activated methylene reagents and curable compositions prepared therefrom LOCTITE R & D LTD 2010-11-24 CN disclosed
EP-2217557-A2 ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM Loctite (R & D) Limited (IE) 2010-08-18 EP disclosed
US-20100199888-A1 ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM LOCTITE (R&D) LIMITED (IE) 2010-08-12 US disclosed
WO-2009053482-A2 ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM LOCTITE (R & D) LIMITED (IE) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11639330-B2 Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium AFF1, PHOSPHO1, CHRM1 ALDH1A1 3194/4885TP53 4006/4885CYP3A4 2259/4885
US-20100199888-A1 ACTIVATED METHYLENE REAGENTS AND CURABLE COMPOSITIONS PREPARED THEREFROM NOTUM, WASF2, BHMT2 ALDH1A1 876/4885TP53 3491/4885CYP3A4 1926/4885
US-10913708-B2 Process for preparing electron deficient olefin precursors COASY, ETFA, PCCA ALDH1A1 607/4885TP53 4669/4885CYP3A4 136/4885
US-10889542-B2 Process for preparing electron deficient olefins COASY, ACSL4, PCCA ALDH1A1 1475/4885TP53 4734/4885CYP3A4 227/4885
US-10913707-B2 Process for preparing electron deficient olefins PCCA, ACSL4, COASY ALDH1A1 1279/4885TP53 4714/4885CYP3A4 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.