Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452208 | 0.76 | MAP3K14 (0.37) | GAAALDH1A1 | |
| SCHEMBL30452454 | 0.75 | MAP3K14 (0.36) | GAAALDH1A1 | |
| SCHEMBL11312148 | 0.73 | ALOX12 (0.34) | ALOX12SIGMAR1GAA | |
| SCHEMBL3267624 | 0.70 | KDM4E (0.47) | ALOX12LMNAOPRM1OPRD1OPRK1 | |
| SCHEMBL27857223 | 0.70 | ALOX12 (0.39) | ALOX12SIGMAR1 | |
| SCHEMBL15084239 | 0.69 | ALDH1A1 (0.41) | ALOX12ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL28167584 | 0.68 | HTR2A (0.47) | ALOX12SIGMAR1ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5179163 | 0.68 | CHRM2 (0.38) | — | |
| SCHEMBL22175918 | 0.68 | SIGMAR1 (0.50) | ALOX12LMNASIGMAR1 | |
| SCHEMBL15975017 | 0.68 | LMNA (0.42) | LMNASIGMAR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854700-A | Isoindolone spiroisochromene compound and synthesis method thereof | 江苏师范大学 | 2023-10-10 | — | — | CN | disclosed |