Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912524 | 0.91 | RAB9A (0.44) | HDAC3HDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL2912906 | 0.81 | CYP3A4 (0.39) | TRPV1EPHX2NR1H4 | |
| SCHEMBL2913166 | 0.81 | XDH (0.38) | MEN1KMT2AALDH1A1NPSR1RAB9A | |
| SCHEMBL2910649 | 0.80 | TDP2 (0.33) | ALDH1A1TRPV1EPHX2NR1H4 | |
| SCHEMBL2908324 | 0.80 | TRPV1 (0.39) | ALDH1A1SMN1; SMN2HPGDTRPV1LMNA | |
| SCHEMBL2915428 | 0.80 | RAB9A (0.40) | MEN1KMT2AALDH1A1NPSR1RAB9A | |
| SCHEMBL1530649 | 0.79 | AURKB (0.51) | CA1CA2HDAC3HDAC6MEN1 | |
| SCHEMBL2910562 | 0.78 | HPGD (0.41) | MEN1KMT2AALDH1A1NPSR1RAB9A | |
| SCHEMBL2917131 | 0.77 | NSD2 (0.39) | CA1CA9MEN1KMT2AALDH1A1 | |
| SCHEMBL2907804 | 0.76 | XDH (0.39) | CA1CA2CA9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |