Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 7/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | HTR6 | P50406 | 5/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 6/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.46 |
| ▸ | HTR3B | O95264 | 3/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30663734 | 1.00 | HTR7 (0.67) | HTR7HTR1AHTR6HTR2BHTR1B | |
| SCHEMBL14060577 | 0.81 | HTR7 (1.00) | HTR7HTR1AHTR6HTR2BHTR1B | |
| Hydrochloric Acid SCHEMBL7921826 | 0.79 | HTR7 (0.97) | HTR7HTR1AHTR6HTR2BHTR1B | |
| SCHEMBL7624639 | 0.74 | HDAC4 (0.46) | — | |
| SCHEMBL29055178 | 0.69 | PTGS2 (0.47) | HTR7HTR1ACYP2C19 | |
| SCHEMBL29057975 | 0.68 | HTR6 (0.59) | HTR7HTR1AHTR6HTR2BHTR1B | |
| SCHEMBL5200437 | 0.68 | HTR6 (0.58) | HTR7HTR1AHTR6HTR3AHTR3E | |
| SCHEMBL547174 | 0.67 | HTR1A (0.77) | HTR7HTR1AHTR6HTR3AHTR3E | |
| SCHEMBL9058690 | 0.67 | ADRB1 (0.89) | HTR7HTR1AHTR6HTR2BHTR1B | |
| SCHEMBL28311434 | 0.67 | HTR6 (0.57) | HTR7HTR1AHTR6HTR2BHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108999-B | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-114920704-B | Phenyl piperazine quinazoline compound or pharmaceutically acceptable salt thereof, preparation method and application | 暨南大学 | 2023-11-03 | — | — | CN | disclosed |