Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21803243 | 0.79 | GSK3B (0.44) | GSK3BTP53PPARGRAB9A | |
| SCHEMBL29107250 | 0.78 | PPARG (0.41) | TP53PPARG | |
| Iodide SCHEMBL28993212 | 0.78 | GSK3B (0.43) | GSK3BTP53PPARGRAB9A | |
| SCHEMBL29107251 | 0.77 | PPARG (0.40) | MEN1KMT2AMAPTGSK3BHDAC6 | |
| SCHEMBL29107246 | 0.77 | SMN1; SMN2 (0.48) | MEN1KMT2AMAPTTP53PPARG | |
| SCHEMBL21449136 | 0.76 | HDAC6 (0.69) | MAPTHDAC6HDAC1TP53HDAC3 | |
| SCHEMBL29107254 | 0.75 | DRD2 (0.41) | MEN1KMT2AMAPTGSK3BHDAC6 | |
| SCHEMBL29107249 | 0.74 | GSK3B (0.40) | MEN1KMT2AMAPTGSK3BTP53 | |
| SCHEMBL29107247 | 0.74 | CHRM5 (0.43) | SIRT1MAPTGSK3BHDAC6HDAC1 | |
| SCHEMBL3970143 | 0.72 | HDAC1 (0.72) | SIRT1MAPTHDAC6HDAC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069742-A | Spiro [ pyridine-thiazolidine ] compound and preparation method and application thereof | 五邑大学 | 2023-11-17 | — | — | CN | disclosed |