Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470557 | 0.81 | HSD11B1 (0.50) | GSTO1AKT1MEN1KMT2ALMNA | |
| SCHEMBL8743153 | 0.81 | GSTO1 (0.47) | TRPM8GSTO1AKT1LMNAALDH1A1 | |
| SCHEMBL29155492 | 0.80 | AKT1 (0.43) | TRPM8GSTO1AKT1MEN1KMT2A | |
| SCHEMBL29155488 | 0.79 | SMN1; SMN2 (0.38) | GSTO1AKT1MEN1KMT2ALMNA | |
| SCHEMBL29155487 | 0.79 | SMN1; SMN2 (0.38) | GSTO1AKT1MEN1KMT2ALMNA | |
| SCHEMBL295841 | 0.73 | LMNA (0.53) | GSTO1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL29155485 | 0.71 | BCL2A1 (0.45) | MTNR1AALDH1A1 | |
| SCHEMBL29155486 | 0.71 | TAS2R14 (0.44) | TRPM8MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL13198360 | 0.71 | GSTO1 (0.47) | TRPM8GSTO1MEN1KMT2ALMNA | |
| SCHEMBL28159112 | 0.71 | ALOX5 (0.50) | TRPM8GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024400-A | Preparation method of aromatic heterocyclic ring-containing enamide derivative | 赣南师范大学 | 2023-11-10 | — | — | CN | disclosed |