Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29155487 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2GAAGSTO1ACKR3LMNA | |
| SCHEMBL29155484 | 0.79 | TRPM8 (0.41) | GSTO1LMNAMAPTHDAC3HDAC1 | |
| SCHEMBL28470557 | 0.73 | HSD11B1 (0.50) | GAAGSTO1LMNAHDAC3HDAC1 | |
| SCHEMBL8743153 | 0.73 | GSTO1 (0.47) | GAAGSTO1LMNARAB9ANPC1 | |
| SCHEMBL29155492 | 0.72 | AKT1 (0.43) | GSTO1LMNARAB9AMAPTNPC1 | |
| SCHEMBL295841 | 0.66 | LMNA (0.53) | SMN1; SMN2GAAGSTO1LMNARAB9A | |
| SCHEMBL29155486 | 0.64 | TAS2R14 (0.44) | SMN1; SMN2LMNARAB9AMAPTNPC1 | |
| SCHEMBL29155485 | 0.64 | BCL2A1 (0.45) | ACKR3RAB9ANPC1ALDH1A1 | |
| SCHEMBL13198360 | 0.64 | GSTO1 (0.47) | GSTO1LMNARAB9ANPC1KMT2A | |
| SCHEMBL28159112 | 0.64 | ALOX5 (0.50) | GSTO1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024400-A | Preparation method of aromatic heterocyclic ring-containing enamide derivative | 赣南师范大学 | 2023-11-10 | — | — | CN | disclosed |