Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 7/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2915217 | 0.87 | CYP3A4 (0.42) | ALOX12ADRB1NTRK1CYP3A4 | |
| SCHEMBL2913166 | 0.81 | XDH (0.38) | TRPV1 | |
| SCHEMBL2915428 | 0.80 | RAB9A (0.40) | ADRB1TRPV1EPHX2NR1H4 | |
| SCHEMBL1530918 | 0.80 | DDB1 (0.37) | ALOX12ADRB1TRPV1EPHX2NR1H4 | |
| SCHEMBL2915358 | 0.79 | ACLY (0.32) | — | |
| SCHEMBL2113416 | 0.78 | CYP3A4 (0.56) | ADRB1CYP3A4 | |
| SCHEMBL2915218 | 0.77 | CYP3A4 (0.40) | ADRB1EPHX2NR1H4CYP3A4 | |
| SCHEMBL2915585 | 0.77 | CYP3A4 (0.43) | ADRB1CYP3A4 | |
| SCHEMBL2907804 | 0.75 | XDH (0.39) | — | |
| SCHEMBL2914859 | 0.74 | CYP3A4 (0.40) | ADRB1EPHX2NR1H4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |