Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916163 | 0.90 | CRBN (0.38) | NR3C2 | |
| SCHEMBL2913166 | 0.86 | XDH (0.38) | NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL2915264 | 0.85 | MAOB (0.37) | NPC1ALDH1A1LMNA | |
| SCHEMBL2910962 | 0.81 | RAB9A (0.39) | NPC1ALDH1A1LMNATP53NPSR1 | |
| SCHEMBL1530700 | 0.81 | KDM4E (0.40) | ACLYNR3C2PDK1ALDH1A1PTGS2 | |
| SCHEMBL2915428 | 0.79 | RAB9A (0.40) | NPC1ALDH1A1LMNANPSR1 | |
| SCHEMBL2915916 | 0.79 | CRBN (0.39) | NR3C2NPC1NPSR1 | |
| SCHEMBL2916119 | 0.79 | ALOX12 (0.37) | — | |
| SCHEMBL2914837 | 0.78 | KMT2A (0.41) | NPC1ALDH1A1 | |
| SCHEMBL2913446 | 0.77 | ALDH1A1 (0.36) | NPC1ALDH1A1LMNATP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |