Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30864097 | 0.92 | GPR119 (0.39) | KMT2A | |
| SCHEMBL31677318 | 0.92 | SMYD3 (0.34) | TSHRTNKSPARP1PARP10TNKS2 | |
| SCHEMBL31677350 | 0.92 | TSHR (0.35) | TSHRTNKSPARP1PARP10TNKS2 | |
| SCHEMBL29201756 | 0.90 | KMT2A (0.37) | TSHRDDR1MGLLCHRM4NPSR1 | |
| SCHEMBL31677282 | 0.89 | ACHE (0.42) | TSHRNPSR1 | |
| SCHEMBL29201746 | 0.87 | MGLL (0.39) | TSHRMGLLNPSR1 | |
| SCHEMBL29277059 | 0.84 | HSD11B1 (0.39) | TSHRMGLLNPSR1HTR1A | |
| SCHEMBL31677332 | 0.83 | MGLL (0.34) | TSHRMGLLLIPGKMT2A | |
| SCHEMBL27143092 | 0.83 | MGLL (0.42) | TSHRMGLLLIPGNPSR1 | |
| SCHEMBL30864109 | 0.83 | GPR119 (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |