SCHEMBL2926533

SCHEMBL2926533

Nc1nc(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)O)O2)cc1CO

nearest known ligand 0.65

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
POLG P54098 1/20 0.51
DNMT1 P26358 4/20 0.50
P2RY2 P41231 2/20 0.50
P2RY4 P51582 2/20 0.50
P2RY6 Q15077 2/20 0.50
DNMT3B Q9UBC3 1/20 0.48
TYMS P04818 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14660974 1.00 POLB (0.55) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL20906737 0.98 POLG (0.54) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL15201233 0.98 POLG (0.54) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL15810651 0.98 POLG (0.54) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL336251 0.98 POLG (0.54) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL22300298 0.98 POLG (0.54) POLBPOLGDNMT1P2RY2P2RY4
SCHEMBL336318 0.92 TYMS (0.55) POLBDNMT1DNMT3BTYMS
SCHEMBL1331043 0.92 TYMS (0.55) POLBDNMT1DNMT3BTYMS
SCHEMBL15472378 0.92 P2RY2 (0.51) POLBPOLGDNMT1P2RY2P2RY4
Triphosphate SCHEMBL28135309 0.90 DNMT1 (0.58) POLBPOLGDNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-07 US disclosed
US-12595509-B2 Synthetic nucleic acid spike-ins KARIUS, INC. (US) 2026-04-07 US disclosed
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-12 US disclosed
US-12553085-B2 Sequencing kit OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-02-17 US disclosed
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY UNIV OXFORD INNOVATION LTD (GB) 2026-02-12 US disclosed
US-20260028379-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-01-29 US disclosed
US-12509721-B2 Methods and systems for characterizing analytes using nanopores OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-12-30 US disclosed
EP-4665753-A1 ARMOURED REGULATORY T CELL King's College London (GB) 2025-12-24 EP disclosed
US-20250361502-A1 Promoters And Compositions UNIV OXFORD INNOVATION LTD (GB) 2025-11-27 US disclosed
EP-4643130-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY Oxford University Innovation Limited (GB) 2025-11-05 EP disclosed
WO-2014170661-A1 STRAIN OF DEFORMED WING VIRUS (DWV) THE UNIVERSITY OF WARWICK (GB) 2014-10-23 WO disclosed
WO-2014102539-A1 DELIVERY METHOD USING MESOPOROUS SILICA NANOPARTICLES ISIS INNOVATION LIMITED (GB) 2014-07-03 WO disclosed
EP-2737084-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES Oxford Nanopore Technologies Limited (GB) 2014-06-04 EP disclosed
WO-2014072703-A1 QUADRUPLEX METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-05-15 WO disclosed
WO-2014064444-A1 DROPLET INTERFACES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2014-05-01 WO disclosed
WO-2013153359-A1 MUTANT LYSENIN PORES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-10-17 WO disclosed
WO-2013121224-A1 ANALYSIS OF MEASUREMENTS OF A POLYMER OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-08-22 WO disclosed
WO-2013121201-A1 APTAMER METHOD OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-08-22 WO disclosed
WO-2013014451-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES OXFORD NANOPORE TECHNOLOGIES LIMITED (GB) 2013-01-31 WO disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE NUP210, EPCAM, PHAX POLB 1826/4885POLG 2862/4885DNMT1 2398/4885
US-12509721-B2 Methods and systems for characterizing analytes using nanopores DNA2, MTREX, DDX21 POLB 48/4885POLG 109/4885DNMT1 123/4885
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY DDX6, DDX1, DDB1 POLB 647/4885POLG 897/4885DNMT1 679/4885
US-12553085-B2 Sequencing kit PHAX, TIA1, POLM POLB 684/4885POLG 1113/4885DNMT1 1190/4885
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES POLRMT, PITPNB, NUP205 POLB 81/4885POLG 528/4885DNMT1 959/4885
US-20260028379-A1 MUTANT PORE PTMS, NUP50, NUP205 POLB 2195/4885POLG 1615/4885DNMT1 2912/4885
US-12595509-B2 Synthetic nucleic acid spike-ins SPOUT1, NOP2, METTL16 POLB 594/4885POLG 2216/4885DNMT1 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.