Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559919 | 0.75 | ALDH1A1 (0.40) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL30751791 | 0.75 | ALDH1A1 (0.40) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL4013841 | 0.72 | KDM4E (0.51) | ALDH1A1POLBSMN1; SMN2HPGDRECQL | |
| SCHEMBL677194 | 0.72 | L3MBTL1 (0.45) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL15691383 | 0.70 | ALDH1A1 (0.39) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL1627774 | 0.69 | HTT (0.38) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL6569026 | 0.68 | ALDH1A1 (0.41) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL3828718 | 0.68 | ALDH1A1 (0.44) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL1721807 | 0.68 | PSMD14 (0.40) | LMNAALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL1261198 | 0.68 | NOS2 (0.54) | LMNAALDH1A1POLBSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940849-B1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2010-01-27 | — | — | EP | disclosed |
| EP-1915344-B1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | BASF SE (DE) | 2008-09-18 | — | — | US | disclosed |
| US-20080207447-A1 | Cyanopyridine Pesticides | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-28 | — | — | US | disclosed |
| EP-1940849-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2008-07-09 | — | — | EP | disclosed |
| EP-1915344-A1 | CYANOPYRIDINE PESTICIDES | BASF SE (DE) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007045588-A1 | ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2007014913-A1 | CYANOPYRIDINE PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227636-A1 | Isothiazolopyridin-3-Ylenamines for Combating Animal Pests | IPO5, PIR, ACHE | LMNA 3877/4885ALDH1A1 2385/4885POLB 4741/4885 |
| US-20080207447-A1 | Cyanopyridine Pesticides | CBR3, CBR1, CHRM1 | LMNA 1153/4885ALDH1A1 3463/4885POLB 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.