SCHEMBL1502176

SCHEMBL1502176

O=P(c1ccccc1)(c1ccccc1)c1cccc(S(=O)(=O)[O-])c1.[Na+]

nearest known ligand 0.62

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGF1 known ✓ P05230 1/20 0.36
▸ CA12 known ✓ O43570 2/20 0.36
▸ CA1 known ✓ P00915 2/20 0.36
▸ CA2 known ✓ P00918 2/20 0.36
▸ CA4 known ✓ P22748 2/20 0.36
▸ KMT2A Q03164 3/20 0.62
▸ POLB P06746 1/20 0.62
▸ APOBEC3A P31941 1/20 0.62
▸ CASP6 P55212 1/20 0.62
▸ CTDSP1 Q9GZU7 1/20 0.62
▸ APOBEC3G Q9HC16 1/20 0.62
▸ DUSP3 P51452 1/20 0.41
▸ PTPN5 P54829 1/20 0.41
▸ PTPN11 Q06124 1/20 0.41
▸ LMNA P02545 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ DUSP5 Q16690 2/20 0.37
▸ RAD51 Q06609 1/20 0.37
▸ PTPN1 P18031 2/20 0.36
▸ CA5A P35218 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15698201 0.83 HTR6 (0.50) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL2928727 0.80 TSHR (0.54) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL29176807 0.80 TSHR (0.54) KMT2APOLBAPOBEC3ACASP6CTDSP1
Water SCHEMBL28691883 0.79 KMT2A (0.54) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL29010460 0.79 CA12 (0.57) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL1502178 0.79 TSHR (0.52) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL31124571 0.77 PTPN1 (0.51) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL28513070 0.77 PTPN1 (0.51) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL128235 0.76 LMNA (0.56) KMT2APOLBAPOBEC3ACASP6CTDSP1
SCHEMBL3181571 0.76 LMNA (0.48) KMT2ALMNATDP1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4222141-B1 LOW REACTIVITY HYDROCARBON DISPERSING AGENTS IN THE AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS CHEMOURS CO FC LLC (US) 2025-08-06 — — EP disclosed
US-20240002553-A1 EMPLOYING LOW REACTIVITY HYDROCARBON DISPERSING AGENT IN AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS THE CHEMOURS COMPANY FC, LLC (US) 2024-01-04 — — US disclosed
EP-4222141-A1 LOW REACTIVITY HYDROCARBON DISPERSING AGENTS IN THE AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS The Chemours Company FC, LLC (US) 2023-08-09 — — EP disclosed
CN-116234794-A Low reactivity hydrocarbon dispersants in aqueous polymerization of fluoropolymers 科慕埃弗西有限公司 2023-06-06 — — CN disclosed
WO-2022072693-A1 LOW REACTIVITY HYDROCARBON DISPERSING AGENTS IN THE AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS THE CHEMOURS COMPANY FC, LLC (US) 2022-04-07 — — WO disclosed
EP-2231682-B1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-06 — — EP disclosed
US-8394978-B2 Sulfonated organophosphine compounds and use thereof in hydroformylation processes DOW GLOBAL TECHNOLOGIES LLC (US) 2013-03-12 — — US disclosed
US-20110054205-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2011-03-03 — — US disclosed
EP-2231682-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES Dow Global Technologies Inc. (US) 2010-09-29 — — EP disclosed
WO-2009091671-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES DOW GLOBAL TECHNOLOGIES INC. (US) 2009-07-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110054205-A1 SULFONATED ORGANOPHOSPHINE COMPOUNDS AND USE THEREOF IN HYDROFORMYLATION PROCESSES IP6K3, ALK, GRK1 FGF1 3953/4885CA12 971/4885CA1 1367/4885
US-20240002553-A1 EMPLOYING LOW REACTIVITY HYDROCARBON DISPERSING AGENT IN AQUEOUS POLYMERIZATION OF FLUOROPOLYMERS FPR1, NAF1, SIGMAR1 FGF1 2792/4885CA12 3879/4885CA1 3780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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