SCHEMBL2929686

SCHEMBL2929686

CCC1Cc2ccccc2C1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.48
IDO1 P14902 3/20 0.47
CYP19A1 P11511 2/20 0.47
ADRA2A P08913 1/20 0.41
HTR1A P08908 1/20 0.41
SIGMAR1 Q99720 1/20 0.39
HTR2A P28223 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL6990432 0.93 DRD3 (0.44) DRD3IDO1CYP19A1ADRA2AHTR1A
SCHEMBL599314 0.84 CYP19A1 (0.54) CYP19A1HTR1ASIGMAR1
SCHEMBL3916886 0.80 FYN (0.57) DRD3IDO1CYP19A1ADRA2AHTR1A
SCHEMBL18322481 0.80 PNMT (0.41) DRD3
Hydrochloric Acid SCHEMBL18706948 0.78 PNMT (0.40) DRD3IDO1
SCHEMBL27520710 0.75 HTR7 (0.51) HTR1A
SCHEMBL13572976 0.75 SIGMAR1 (0.52) HTR1ASIGMAR1
SCHEMBL13291929 0.75 DRD3 (0.48) DRD3CYP19A1ADRA2AHTR1AHTR2A
SCHEMBL32686719 0.75 DRD2 (0.48) DRD3HTR1A
SCHEMBL13572973 0.75 SIGMAR1 (0.52) HTR1ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10913902-B2 Production of high energy-dense liquid hydrocarbon from low energy-dense aqueous solutions of oxygen containing organic compound(s) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2021-02-09 US claimed
US-20200056099-A1 PRODUCTION OF HIGH ENERGY-DENSE LIQUID HYDROCARBON FROM LOW ENERGY-DENSE AQUEOUS SOLUTIONS OF OXYGEN CONTAINING ORGANIC COMPOUND(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-02-20 US claimed
US-20260080976-A1 SYSTEM AND METHODS FOR GENERATION OF FRAGMENT MODULE LIBRARIES FOR LEAD OPTIMIZATION OF PHARMACEUTICALLY ACTIVE MOLECULES PURDUE RESEARCH FOUNDATION (US) 2026-03-19 US disclosed
US-12414937-B2 Local and regional anesthesia and analgesia UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2025-09-16 US disclosed
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed
CN-115768740-A Process for preparing indene acrolein derivative 弗门尼舍有限公司 2023-03-07 CN disclosed
EP-3904354-A1 NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 Perha Pharmaceuticals (FR) 2021-11-03 EP disclosed
US-10913902-B2 Production of high energy-dense liquid hydrocarbon from low energy-dense aqueous solutions of oxygen containing organic compound(s) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2021-02-09 US disclosed
WO-2021020429-A1 UREA COMPOUND FOR ANTAGONIZING LPA1 RECEPTOR 大正製薬株式会社 2021-02-04 WO disclosed
US-20200056099-A1 PRODUCTION OF HIGH ENERGY-DENSE LIQUID HYDROCARBON FROM LOW ENERGY-DENSE AQUEOUS SOLUTIONS OF OXYGEN CONTAINING ORGANIC COMPOUND(S) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2020-02-20 US disclosed
EP-1888502-B1 CATALYTIC SCRIABINE REACTION FIRMENICH & CIE (CH) 2016-07-13 EP disclosed
EP-1675824-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS Oy Juvantia Pharma Ltd (FI) 2006-07-05 EP disclosed
WO-2005056520-A1 SOMATOSTATIN RECEPTOR SUBTYPE 1 (SSTR1) ACTIVE COMPOUNDS AND THEIR USE IN THERAPY OY JUVANTIA PHARMA LTD (FI) 2005-06-23 WO disclosed
WO-2005033068-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 WO disclosed
WO-2005033069-A1 SOMATOSTATIN RECEPTOR 1 AND/OR 4 SELECTIVE AGONISTS AND ANTAGONISTS OY JUVANTIA PHARMA LTD (FI) 2005-04-14 WO disclosed
CN-1113874-C Benzocycloalkylazolethione derivatives SYNTEX INC (US) 2003-07-09 CN disclosed
CN-1151735-A Benzocycloalkylazolethione derivatives SYNTEX INC (US) 1997-06-11 CN disclosed
US-4182896-A ANTIINFLAMMATORY AGENTS, ANALGESICS SOCIETE HEXACHIMIE (FR) 1980-01-08 US disclosed
US-4166131-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT HEXACHIMIE SOCIETE ANONYME (FR) 1979-08-28 US disclosed
US-3939095-A PHENYLINDANES, ADDITION COPOLYMERS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250106-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 DRD3 4705/4885IDO1 1263/4885CYP19A1 3649/4885
US-20260080976-A1 SYSTEM AND METHODS FOR GENERATION OF FRAGMENT MODULE LIBRARIES FOR LEAD OPTIMIZATION OF PHARMACEUTICALLY ACTIVE MOLECULES BACE2, ADAM33, SET DRD3 300/4885IDO1 3262/4885CYP19A1 1689/4885
US-12414937-B2 Local and regional anesthesia and analgesia OPRL1, OPRK1, OPRM1 DRD3 622/4885IDO1 1093/4885CYP19A1 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.