SCHEMBL29316305

SCHEMBL29316305

CC(O[SiH](C)CCc1ccccc1)[SiH](C)O[SiH](C)CCc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
AOC3 Q16853 1/20 0.33
TAAR1 Q96RJ0 3/20 0.32
SLC6A2 P23975 2/20 0.32
MAOA P21397 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ATM Q13315 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18389643 0.77 ALDH1A1 (0.39) ALDH1A1AOC3TAAR1MAOAATM
SCHEMBL28914812 0.76 ALDH1A1 (0.35) SIGMAR1ALDH1A1AOC3TAAR1ATM
SCHEMBL338863 0.71 ALDH1A1 (0.41) ALDH1A1AOC3TAAR1MAOAATM
SCHEMBL837631 0.71 ALDH1A1 (0.41) ALDH1A1AOC3TAAR1ATMCYP2A6
SCHEMBL1325408 0.69 MAOA (0.43) SIGMAR1ALDH1A1AOC3TAAR1SLC6A2
SCHEMBL3342114 0.68 TP53 (0.39) SIGMAR1ALDH1A1AOC3TAAR1SLC6A2
SCHEMBL17519998 0.67 ALDH1A1 (0.37) SIGMAR1ALDH1A1AOC3TAAR1ATM
SCHEMBL7749434 0.66 ALDH1A1 (0.48) ALDH1A1AOC3TAAR1MAOAATM
SCHEMBL476138 0.66 TP53 (0.50) ALDH1A1AOC3TAAR1MAOAATM
SCHEMBL3482599 0.66 IDO1 (0.37) SIGMAR1ALDH1A1AOC3TAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3323505-B1 HYDROSILYLATION REACTION CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-07-17 EP disclosed