Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 6/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.39 |
| ▸ | APOB | P04114 | 3/20 | 0.38 |
| ▸ | MTTP | P55157 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2930955 | 0.92 | HCRTR2 (0.38) | HCRTR2HCRTR1APOBMTTPPIK3CD | |
| SCHEMBL2924244 | 0.91 | CYP46A1 (0.39) | HCRTR2HCRTR1P2RX7PIK3CDCYP46A1 | |
| SCHEMBL2931040 | 0.91 | HCRTR2 (0.40) | HCRTR2HCRTR1HSD11B1PIK3CDMEN1 | |
| SCHEMBL2928151 | 0.90 | HCRTR2 (0.35) | HCRTR2HCRTR1 | |
| SCHEMBL2931912 | 0.86 | APOB (0.38) | HCRTR2HCRTR1APOBMTTPP2RX7 | |
| SCHEMBL2925493 | 0.85 | HCRTR2 (0.37) | HCRTR2HCRTR1PIK3CD | |
| SCHEMBL2930744 | 0.85 | HCRTR2 (0.37) | HCRTR2HCRTR1PIK3CDCYP46A1 | |
| SCHEMBL2930074 | 0.84 | SLC6A7 (0.35) | HCRTR2HCRTR1 | |
| SCHEMBL2925368 | 0.84 | HCRTR1 (0.41) | HCRTR2HCRTR1 | |
| SCHEMBL2932494 | 0.83 | HCRTR2 (0.38) | HCRTR2HCRTR1CYP46A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079690-B1 | 3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-15 | — | — | EP | disclosed |