Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trypan Blue Free Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | TST | Q16762 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GRK2 | P25098 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trypan Blue Free Acid SCHEMBL29371631 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL31686853 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL9724 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29637809 | 0.91 | PTPN1 (0.83) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29637844 | 0.90 | PTPN1 (0.81) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29601587 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29402157 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL20496488 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL9222420 | 0.87 | PTPN1 (0.77) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL15497820 | 0.85 | MEN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120134391-A | Automatic bale splitter of hollow fiber membrane | 山东百川精密科技有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119971776-A | Ultrafiltration membrane glue filling device and glue filling method thereof | 常州市美纤膜技术有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-222678627-U | Diaphragm glue spreader of gas meter | 龙口振华仪表科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119243874-A | Cable net structure for ultra-large span inflatable membrane structure and layout method thereof | 中电建路桥集团有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-119217742-A | Automatic production system for ultrafiltration membrane glue injection and cutting | 南京工程学院 | 2024-12-31 | — | — | CN | claimed |
| CN-118970220-A | Composite electrolyte for inhibiting hydrogen evolution reaction and manufacturing method of zinc-manganese cylindrical battery | 江苏通灵电器股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-221641999-U | Composite film with humidifying performance | 云南名博实业有限公司 | 2024-09-03 | — | — | CN | claimed |
| CN-221378119-U | Electrical detection device convenient to carry | 天津乐鸟智慧科技有限责任公司 | 2024-07-19 | — | — | CN | claimed |
| CN-221311279-U | Rupture membrane glue coating machine | 武汉简一科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-220941493-U | Equipment is paintd to building waterproofing membrane glue solution | 鹏腾(山东)防水材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-112610433-B | Forward osmosis-electric salt difference energy efficient continuous power generation device based on porous medium | 南京工业大学 | 2022-05-03 | — | — | CN | claimed |
| CN-216423688-U | High-toughness tensile wear-resistant knitted fabric | 石狮市万得福漂染织造有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-216330427-U | Automatic multi-page film laminating machine | 深圳市世椿智能装备股份有限公司 | 2022-04-19 | — | — | CN | claimed |
| CN-114335671-A | Pole piece compound mechanism and lamination device | 三一技术装备有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-106956543-B | Manufacturing process of emerald feather silver wire and emerald feather silver wire | 谢晶 | 2022-04-12 | — | — | CN | claimed |
| CN-216106717-U | Curved surface screen protection film | 深圳市柏铭达科技有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-216032346-U | Drench membrane flue gas recovery unit | 滨州英宏包装制品有限公司 | 2022-03-15 | — | — | CN | claimed |
| CN-215878552-U | Tubular membrane glue-pouring device | 波塞冬(江苏)新材料科技有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-114034031-A | Raw flue gas hydrothermal utilization system based on ceramic membrane flue gas hydrothermal trapping device | 华北电力大学 | 2022-02-11 | — | — | CN | claimed |
| CN-114024014-A | Lamination system of battery core pole piece | 三一技术装备有限公司 | 2022-02-08 | — | — | CN | claimed |