Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trypan Blue Free Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.63 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.55 |
| ▸ | TST | Q16762 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GRK2 | P25098 | 1/20 | 0.53 |
| ▸ | PLEC | Q15149 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trypan Blue Free Acid SCHEMBL29350476 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL29371631 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL31686853 | 1.00 | PTPN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29637809 | 0.91 | PTPN1 (0.83) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29637844 | 0.90 | PTPN1 (0.81) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29601587 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL29402157 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL20496488 | 0.88 | PTPN1 (0.79) | PTPN1USP2ATML3MBTL1MEN1 | |
| SCHEMBL9222420 | 0.87 | PTPN1 (0.77) | PTPN1USP2ATML3MBTL1MEN1 | |
| Trypan Blue Free Acid SCHEMBL15497820 | 0.85 | MEN1 (1.00) | PTPN1USP2ATML3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 123714 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748304-A2 | SYSTEM AND METHOD FOR IDENTIFYING BLOOD VESSELS DURING FLUORESCENCE IMAGING | Perfusion Tech ApS (DK) | 2026-05-27 | — | — | EP | claimed |
| CN-115837073-B | Preparation method and application of swine Senicavirus disease inactivated vaccine | 中牧实业股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012378-A | Suspension serum-free PK cell based on composite synergist and method for culturing porcine circovirus by using suspension serum-free PK cell | 北京鼎持生物技术有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260096736-A1 | SYSTEM AND METHOD FOR IDENTIFYING AN ABNORMAL PERFUSION PATTERN | PERFUSION TECH APS (DK) | 2026-04-09 | — | — | US | claimed |
| EP-4719655-A2 | MICROCAPSULE CROSSLINKING | Droplet Genomics, Uab (LT) | 2026-04-08 | — | — | EP | claimed |
| EP-4704870-A1 | RETINAL PIGMENT EPITHELIUM CELL THERAPY | The Regents of University of California (US) | 2026-03-11 | — | — | EP | claimed |
| US-12569371-B2 | Sterilization of medical dressings with enhanced antimicrobial properties | HYDROFERA, LLC (US) | 2026-03-10 | — | — | US | claimed |
| CN-119366384-B | Method for improving black shank resistance of tobacco | 浙江中烟工业有限责任公司 | 2026-02-27 | — | — | CN | claimed |
| US-12559629-B2 | Method for preparing a stable Trypan Blue solution | BECKMAN COULTER, INC. (US) | 2026-02-24 | — | — | US | claimed |
| US-20260048152-A1 | GEMCITABINE INORGANIC-ORGANIC HYBRID NANOPARTICLES | KARLSRUHER INSTITUT FUER TECH KOERPERSCHAFT DES OEFFENTLICHEN RECHTS (DE) | 2026-02-19 | — | — | US | claimed |
| US-4424201-A | Employment of a mereyanine dye for the detection of malignant leukocytic cells | ROCKEFELLER UNIVERSITY (US) | 1984-01-03 | — | — | US | claimed |
| EP-0089365-A1 | New Dye or Fluorescent polymers and their use as labels in immunoassay systems. | PHOTEST DIAGNOSTICS, INC. (US) | 1983-09-28 | — | — | EP | claimed |
| WO-1983001064-A1 | NOVEL PHOTON ABSORBING OR EMITTING POLYMERS AND THEIR USE AS REAGENTS IN IMMUNOASSAY SYSTEMS | HENRY, ROBERT, P. | 1983-03-31 | — | — | WO | claimed |
| EP-0073773-A1 | PERFUSION-CULTIVATION OF ANIMAL CELLS AND EQUIPMENT THEREFOR. | PETERSON ANDERS (SE) | 1983-03-16 | — | — | EP | claimed |
| WO-1982003227-A1 | PERFUSION-CULTIVATION OF ANIMAL CELLS AND EQUIPMENT THEREFOR | PETERSON ANDERS | 1982-09-30 | — | — | WO | claimed |
| EP-0060509-A2 | Perfusion-cultivation of animal cells and equipment therefor | Peterson, Anders (SE) | 1982-09-22 | — | — | EP | claimed |
| EP-0004061-B1 | METHOD FOR DETERMINING LEUKAEMIC CELLS | MERCK PATENT GmbH (DE) | 1982-05-19 | — | — | EP | claimed |
| US-4159203-A | Aqueous black ink and process for the production thereof | OLYMPIA WERKE AG (DE) | 1979-06-26 | — | — | US | claimed |
| US-4025164-A | Liquid crystal display device for colored display of information with a selective polarizer | BBC BROWN BOVERI & COMPANY LIMITED (CH) | 1977-05-24 | — | — | US | claimed |
| US-4025306-A | Process and apparatus for heartworm microfilariae detection | STUDER ARNOLD DAVID | 1977-05-24 | — | — | US | claimed |