SCHEMBL29355944

SCHEMBL29355944

CC(C)[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H](C(=O)O)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 2/20 0.47
▸ DPP8 Q6V1X1 2/20 0.47
▸ DPP9 Q86TI2 2/20 0.47
▸ DPP7 Q9UHL4 2/20 0.47
▸ FAP Q12884 1/20 0.47
▸ SLC7A5 Q01650 1/20 0.45
▸ BACE1 P56817 1/20 0.39
▸ MME P08473 1/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ CA2 P00918 2/20 0.36
▸ CA1 P00915 1/20 0.36
▸ GAA P10253 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ PLA2G2A P14555 1/20 0.36
▸ PLA2G5 P39877 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ FPR2 P25090 1/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Val-Val SCHEMBL28590100 0.92 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP
Val-Val SCHEMBL30582070 0.92 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP
Val-Val SCHEMBL4582286 0.92 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP
Val-Val SCHEMBL4582285 0.92 DPP4 (0.53) DPP4DPP8DPP9DPP7FAP
Val-Val SCHEMBL16027555 0.90 DPP4 (0.52) DPP4DPP8DPP9DPP7FAP
SCHEMBL30567436 0.89 BACE1 (0.38) DPP4DPP8DPP9DPP7FAP
SCHEMBL7344595 0.89 DPP4 (0.50) DPP4DPP8DPP9DPP7FAP
SCHEMBL30862438 0.89 DPP4 (0.50) DPP4DPP8DPP9DPP7FAP
SCHEMBL30862441 0.89 DPP4 (0.50) DPP4DPP8DPP9DPP7FAP
SCHEMBL7344585 0.89 DPP4 (0.50) DPP4DPP8DPP9DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 405 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2026-05-28 — — US claimed
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 — — US claimed
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2026-01-08 — — US claimed
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR BIO THERA SOLUTIONS LTD (CN) 2025-12-18 — — US claimed
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF BIO THERA SOLUTIONS LTD (CN) 2025-10-30 — — US claimed
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-21 — — US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 — — US claimed
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR BIO-THERA SOLUTIONS, LTD. (CN) 2025-08-07 — — US claimed
EP-4556027-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF Bio-Thera Solutions, Ltd. (CN) 2025-05-21 — — EP claimed
EP-4545099-A1 METHOD FOR TREATING SOLID TUMOR Bio-Thera Solutions, Ltd. (CN) 2025-04-30 — — EP claimed
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES IMMUNOGEN, INC. (US) 2023-03-30 — — US claimed
WO-2022253284-A1 DRUG CONJUGATE AND USE THEREOF 百奥泰生物制药股份有限公司 2022-12-08 — — WO claimed
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IMMUNOGEN, INC. 2022-11-24 — — US claimed
CN-106604927-B Cytotoxic benzodiazepine derivatives 伊缪诺金公司 2022-08-09 — — CN claimed
WO-2022150637-A1 NOVEL STEROID PAYLOADS, STEROID LINKERS, ADCs CONTAINING AND USE THEREOF IMMUNEXT, INC. (US) 2022-07-14 — — WO claimed
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IMMUNOGEN, INC. (US) 2022-05-17 — — US claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 — — US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 — — CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 — — EP claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008848-A1 ANTI-NECTIN-4 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF NECTIN4, VSIG8, IGSF11 DPP4 194/4885DPP8 1223/4885DPP9 1567/4885
US-20250249114-A1 METHOD FOR TREATING HER2-POSITIVE SOLID TUMOR ERBB2, EGFR, ERBB3 DPP4 1450/4885DPP8 1553/4885DPP9 1610/4885
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF DPP4 1262/4885DPP8 3390/4885DPP9 2149/4885
US-20260144882-A1 ANTI-NECTIN-4 ANTIBODY DRUG CONJUGATE AND USE THEREOF NECTIN4, CD22, NGFR DPP4 922/4885DPP8 952/4885DPP9 1352/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF DPP4 1262/4885DPP8 3390/4885DPP9 2149/4885
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES GABBR2, GABRB1, GABRB2 DPP4 4586/4885DPP8 4829/4885DPP9 4796/4885
US-20250333498-A1 ANTI-CLDN18.2 ANTIBODY, AND ANTIBODY-DRUG CONJUGATE AND USE THEREOF CNTN1, EPCAM, SLC22A8 DPP4 2383/4885DPP8 359/4885DPP9 1533/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG DPP4 2235/4885DPP8 3838/4885DPP9 3056/4885
US-20250381283-A1 METHOD FOR TREATING SOLID TUMOR TPM4, TPM3, TPST2 DPP4 1914/4885DPP8 1817/4885DPP9 1553/4885
US-20220372152-A1 ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF IL23R, CD22, IL2RA DPP4 2000/4885DPP8 1434/4885DPP9 1081/4885
US-11332535-B2 Anti-CD123 antibodies and conjugates and derivatives thereof IL23R, CD22, IL2RA DPP4 2000/4885DPP8 1434/4885DPP9 1081/4885
US-20250262316-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF FCGR2A, FCGR1A, FCGR3B DPP4 1117/4885DPP8 1503/4885DPP9 524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback