SCHEMBL29367388

SCHEMBL29367388

O=C(O)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.64
MDM4 O15151 3/20 0.60
TP53 P04637 3/20 0.60
KMT2A Q03164 2/20 0.57
MDM2 Q00987 5/20 0.53
SLC17A5 Q9NRA2 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL378040 1.00 CASP3 (0.64) CASP3MDM4TP53KMT2AMDM2
SCHEMBL1486199 1.00 CASP3 (0.64) CASP3MDM4TP53KMT2AMDM2
SCHEMBL30055375 1.00 CASP3 (0.64) CASP3MDM4TP53KMT2AMDM2
SCHEMBL29352428 1.00 CASP3 (0.64) CASP3MDM4TP53KMT2AMDM2
SCHEMBL378041 1.00 CASP3 (0.64) CASP3MDM4TP53KMT2AMDM2
SCHEMBL30988976 0.93 CASP3 (0.56) CASP3MDM4TP53KMT2AMDM2
SCHEMBL29401049 0.92 CASP3 (0.60) CASP3MDM4TP53KMT2AMDM2
SCHEMBL29047043 0.91 CASP3 (0.59) CASP3MDM4TP53KMT2AMDM2
SCHEMBL30656568 0.91 MDM4 (0.59) CASP3MDM4TP53KMT2AMDM2
SCHEMBL29053258 0.91 CASP3 (0.58) CASP3MDM4TP53KMT2AMDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098519-A1 RADIOLIGAND COMPOUNDS AND USES THEREOF Chengdu New Radiomedicine Technology Co., Ltd. (CN) 2026-05-15 WO disclosed
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2026-05-07 US disclosed
US-20260115333-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY PURDUE RESEARCH FOUNDATION (US) 2026-04-30 US disclosed
US-20260115334-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY PURDUE RESEARCH FOUNDATION (US) 2026-04-30 US disclosed
US-20250154197-A1 LIPOLYTIC PEPTIDES FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA (ES) 2025-05-15 US disclosed
WO-2025005639-A1 CATIONIC AMPHIPHILIC POLYPEPTIDE FOR RNA DELIVERY AND MANUFACTURING METHOD THEREOF 인하대학교 산학협력단 2025-01-02 WO disclosed
EP-4482848-A2 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY Purdue Research Foundation (US) 2025-01-01 EP disclosed
US-20240424153-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY PURDUE RESEARCH FOUNDATION 2024-12-26 US disclosed
CN-119072485-A Conjugates, compositions and methods for hydroxyapatite targeted imaging and therapy 普渡研究基金会 2024-12-03 CN disclosed
US-20240382629-A1 HETEROBIVALENT AND HOMOBIVALENT AGENTS TARGETING FIBROBLAST ACTIVATION PROTEIN ALPHA AND/OR PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE JOHNS HOPKINS UNIVERSITY 2024-11-21 US disclosed
US-11560407-B2 FOXP3-binding peptides and uses thereof FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) 2023-01-24 US disclosed
US-20220289792-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2022-09-15 US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-108473483-B Compounds for medical use 奥斯维尔医疗私人有限公司 2022-08-30 CN disclosed
US-20220218852-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2022-07-14 US disclosed
US-20220184222-A1 BICYCLE TOXIN CONJUGATES AND USES THEREOF BICYCLETX LTD (GB) 2022-06-16 US disclosed
CN-114364690-A Novel radiolabeled CXCR4 targeting compounds for diagnosis and therapy 省卫生服务机构 2022-04-15 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
EP-3956346-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY Provincial Health Services Authority (CA) 2022-02-23 EP disclosed
CN-109311910-B Tacrolimus conjugates, compositions thereof, and uses thereof 杜兰教育基金委员会 2022-02-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115334-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY FGF23, FOLH1, HDGF CASP3 982/4885MDM4 3501/4885TP53 621/4885
US-20220184222-A1 BICYCLE TOXIN CONJUGATES AND USES THEREOF EPHA2, EPHB2, EPHB3 CASP3 776/4885MDM4 4871/4885TP53 210/4885
US-20220218852-A1 NOVEL RADIOLABELLED CXCR4-TARGETING COMPOUNDS FOR DIAGNOSIS AND THERAPY CXCR4, CXCR1, FPR1 CASP3 3834/4885MDM4 4011/4885TP53 2939/4885
US-11560407-B2 FOXP3-binding peptides and uses thereof CCR3, CCR4, CXCR3 CASP3 694/4885MDM4 1272/4885TP53 296/4885
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 CASP3 2990/4885MDM4 4213/4885TP53 135/4885
US-20220289792-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 CASP3 3383/4885MDM4 2761/4885TP53 147/4885
US-20240424153-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY CD44, SOST, FGF23 CASP3 661/4885MDM4 1253/4885TP53 49/4885
US-20260115333-A1 CONJUGATES, COMPOSITIONS, AND METHODS FOR HYDROXYAPATITE-TARGETED IMAGING AND THERAPY FGF23, SLC34A2, SLC34A3 CASP3 578/4885MDM4 4565/4885TP53 663/4885
US-20240382629-A1 HETEROBIVALENT AND HOMOBIVALENT AGENTS TARGETING FIBROBLAST ACTIVATION PROTEIN ALPHA AND/OR PROSTATE-SPECIFIC MEMBRANE ANTIGEN FAP, FIBP, FOLH1 CASP3 2460/4885MDM4 1681/4885TP53 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.