Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108989 | 1.00 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL30838803 | 0.98 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL3974202 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL22830483 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL30788403 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL19778900 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL323982 | 0.74 | ALDH1A1 (0.52) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL2493987 | 0.74 | BRD4 (0.51) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL1165562 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 | |
| SCHEMBL29804946 | 0.74 | ALDH1A1 (0.46) | PI4KAPI4K2BPI4K2API4KBLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4677110-A1 | IMPROVED METHOD FOR DETECTING A TARGET VARIANT BASE USING A VARIANT-SPECIFIC PROBE | Rarity Bioscience AB (SE) | 2026-01-14 | — | — | EP | claimed |
| EP-3833715-B1 | SILICON-SUBSTITUTED RHODAMINE DYES AND DYE CONJUGATES | LIFE TECHNOLOGIES CORP (US) | 2026-01-07 | — | — | EP | claimed |
| US-20250320177-A1 | COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORP (US) | 2025-10-16 | — | — | US | claimed |
| CN-119998357-A | Compositions and methods for liquid phase oligonucleotide synthesis | 兆维生物科技公司 | 2025-05-13 | — | — | CN | claimed |
| EP-4543960-A1 | COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | Hongene Biotech Corporation (US) | 2025-04-30 | — | — | EP | claimed |
| WO-2025081542-A1 | GRNA AND BIOSYNTHESIS METHOD THEREFOR | 吉林凯莱英医药化学有限公司 | 2025-04-24 | — | — | WO | claimed |
| WO-2025081543-A1 | RNA CONTAINING PHOSPHOROTHIOATE BOND AND PREPARATION METHOD THEREFOR | 吉林凯莱英医药化学有限公司 | 2025-04-24 | — | — | WO | claimed |
| WO-2025081539-A1 | TRNA AND BIOSYNTHESIS METHOD THEREFOR | 吉林凯莱英医药化学有限公司 | 2025-04-24 | — | — | WO | claimed |
| WO-2025081541-A1 | PREPARATION METHOD FOR NON-NATURAL RNA AND PRODUCT | 吉林凯莱英医药化学有限公司 | 2025-04-24 | — | — | WO | claimed |
| CN-119462803-B | Nucleoside monomer analogue, oligonucleotide synthesis method and application | 天津凯莱英生物科技有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-116903690-A | Nucleoside dimer, preparation method thereof and application thereof in DNA synthesis | 中国人民解放军军事科学院军事医学研究院 | 2023-10-20 | — | — | CN | claimed |
| US-11725073-B2 | Compositions and methods for liquid phase oligonucleotide synthesis | HONGENE BIOTECH CORPORATION (US) | 2023-08-15 | — | — | US | claimed |
| US-20230212209-A1 | COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORPORATION | 2023-07-06 | — | — | US | claimed |
| CN-109661232-B | Nucleotide derivatives and methods of use thereof | 纽约哥伦比亚大学董事会 | 2023-03-03 | — | — | CN | claimed |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | claimed |
| US-20230028388-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-01-26 | — | — | US | claimed |
| US-20220411860-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-12-29 | — | — | US | claimed |
| US-20220298201-A1 | FLUORINATED NUCLEOTIDES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-09-22 | — | — | US | claimed |
| US-20220204670-A1 | COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | HONGENE BIOTECH CORPORATION | 2022-06-30 | — | — | US | claimed |
| CN-108779138-B | Design and synthesis of nucleotides based on novel disulfide linkers for use as reversible terminators for DNA sequencing by synthesis | 哥伦比亚大学董事会 | 2022-06-17 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250320177-A1 | COMPOUNDS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | POLR2H, POLRMT, POLR2E | PI4KA 2006/4885PI4K2B 2227/4885PI4K2A 2210/4885 |
| US-20230212209-A1 | COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | POLR2H, POLR2E, POLI | PI4KA 894/4885PI4K2B 1183/4885PI4K2A 1200/4885 |
| US-20220411860-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | POLL, POLQ, POLB | PI4KA 1619/4885PI4K2B 1385/4885PI4K2A 1499/4885 |
| US-20230028388-A1 | DESIGN AND SYNTHESIS OF NOVEL DISULFIDE LINKER BASED NUCLEOTIDES AS REVERSIBLE TERMINATORS FOR DNA SEQUENCING BY SYNTHESIS | RNGTT, POLRMT, MTR | PI4KA 3406/4885PI4K2B 2863/4885PI4K2A 2484/4885 |
| US-11725073-B2 | Compositions and methods for liquid phase oligonucleotide synthesis | RNGTT, POLR2H, POLI | PI4KA 1133/4885PI4K2B 1640/4885PI4K2A 1374/4885 |
| US-20220204670-A1 | COMPOSITIONS AND METHODS FOR LIQUID PHASE OLIGONUCLEOTIDE SYNTHESIS | RNGTT, POLR2H, POLI | PI4KA 1133/4885PI4K2B 1640/4885PI4K2A 1374/4885 |
| US-20220298201-A1 | FLUORINATED NUCLEOTIDES AND USES THEREOF | NOP2, FBL, RNGTT | PI4KA 1367/4885PI4K2B 1831/4885PI4K2A 1619/4885 |
| US-20230028321-A1 | NUCLEOTIDE DERIVATIVES AND METHODS OF USE THEREOF | POLRMT, NSUN2, NUDT1 | PI4KA 1550/4885PI4K2B 1844/4885PI4K2A 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.