Lactoferricin

Lactoferricin

SCHEMBL29376740

CC[C@H](C)[C@@H]1NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)N[C@H](CCCCN)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)Cc2ccccc2)CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc2ccccc2)C(=O)O)C(C)C)NC(=O)[C@H]([C@@H](C)O)NC1=O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RXFP4 Q8TDU9 5/20 0.60
RXFP3 Q9NSD7 5/20 0.60
GLP1R P43220 2/20 0.57
GCGR P47871 2/20 0.57
RXFP1 Q9HBX9 1/20 0.56
F11 P03951 1/20 0.56
KCNA3 P22001 1/20 0.56
KCNA1 Q09470 1/20 0.56
MC4R P32245 2/20 0.56
MC1R Q01726 2/20 0.56
F12 P00748 4/20 0.56
NECTIN4 Q96NY8 2/20 0.55
KCNMA1 Q12791 1/20 0.55
KCNMB4 Q86W47 1/20 0.55
MC3R P41968 1/20 0.55
NPR1 P16066 1/20 0.54
NPR3 P17342 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28586826 0.98 RXFP4 (0.61) RXFP4RXFP3GLP1RGCGRRXFP1
SCHEMBL29438822 0.78 KCNMA1 (0.66) RXFP4RXFP3RXFP1F11MC4R
SCHEMBL18375845 0.77 EPHA2 (0.58) F12
SCHEMBL18375815 0.77 EPHA2 (0.58) F12
SCHEMBL29467923 0.76 MC4R (0.64) RXFP1F11KCNA3KCNA1MC4R
SCHEMBL29462295 0.76 MC4R (0.70) RXFP1F11MC4RMC1RF12
SCHEMBL29412264 0.76 KCNA3 (0.57) RXFP4RXFP3F11KCNA3KCNA1
SCHEMBL29353028 0.74 F12 (0.57) RXFP1F11MC4RMC1RF12
Acetic Acid SCHEMBL29363649 0.73 NPR1 (0.87) RXFP1F11KCNA3KCNA1MC4R
SCHEMBL30883974 0.73 KLK5 (0.55) RXFP4RXFP3GLP1RGCGRF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260020591-A1 FLAVOR BLENDS COMPRISING BRAZZEIN PERFECT DAY INC (US) 2026-01-22 US claimed
EP-4557971-A1 FLAVOR BLENDS COMPRISING BRAZZEIN Perfect Day, Inc. (US) 2025-05-28 EP claimed
CN-119999770-A Liquid milk and preparation method and application thereof 内蒙古蒙牛乳业(集团)股份有限公司 2025-05-16 CN claimed
EP-4523699-A1 ANTI-INFLAMMATORY DERMATOLOGICAL COMPOSITION COMPRISING GLYCEROPHOSPHOINOSITOL, A LACTOFERRIN HYDROLYSATE AND A CANNABINOID, IN PARTICULAR FOR TREATING SEBORRHEIC DERMATITIS FB Dermo srl (IT) 2025-03-19 EP claimed
US-12208125-B2 Stable dry powders and emulsions containing probiotics VIRUN, INC. (US) 2025-01-28 US claimed
CN-118878701-A Bovine lactoferrin antibacterial peptide modified body and expression and application thereof in pichia pastoris 江南大学 2024-11-01 CN claimed
US-12036267-B2 Lactoferricin and lactoferrampin for treating infections BICT S.R.L. (IT) 2024-07-16 US claimed
US-11951116-B2 Vaginal composition and use thereof SINGAPORE ZE&ZINTERNATIONAL PTE. LTD (SG) 2024-04-09 US claimed
WO-2024049307-A1 MICROBIAL STRAINS, SUBSTRATES, AND SYSTEMS FOR PROTEIN EXPRESSION DAISY LAB LIMITED (NZ) 2024-03-07 WO claimed
CN-115850448-B Lactoferrin polypeptide fragment, preparation method thereof, prepared antibody and application 北京博奥森生物技术有限公司 2024-02-02 CN claimed
US-20230067261-A1 METHODS FOR TREATING INFLAMMATORY CONDITIONS OF THE LUNGS DEFENSIN THERAPEUTICS APS (DK) 2023-03-02 US claimed
US-20230047790-A1 STABLE DRY POWDERS AND EMULSIONS CONTAINING PROBIOTICS VIRUN, INC. 2023-02-16 US claimed
CN-115581219-A Feeding management method for improving health of newborn calves 河北省农林科学院粮油作物研究所 2023-01-10 CN claimed
CN-113354726-B Lactoferrin active peptide and application thereof 南方科技大学 2022-12-27 CN claimed
US-11491194-B2 Stable dry powders and emulsions containing probiotics VIRUN, INC. (US) 2022-11-08 US claimed
US-20220273733-A1 NUTRITIVE COMPOSITIONS WITH BIOACTIVE PROTEINS EVOLVE BIOSYSTEMS INC (US) 2022-09-01 US claimed
US-11413328-B2 Methods for treating inflammatory conditions of the lungs NOVOZYMES A/S (DK) 2022-08-16 US claimed
EP-4003300-A1 NUTRITIVE COMPOSITIONS WITH BIOACTIVE PROTEINS Evolve Biosystems Inc. (US) 2022-06-01 EP claimed
CN-114129553-A anti-HPV bioprotein gel containing garlic extract 安徽德莱康生物医疗科技有限公司 2022-03-04 CN claimed
WO-2022029577-A1 COMPOSITION FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BICT S.R.L. (IT) 2022-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260020591-A1 FLAVOR BLENDS COMPRISING BRAZZEIN TAS2R14, TAS2R60, GPR119 RXFP4 76/4885RXFP3 149/4885GLP1R 17/4885
US-11491194-B2 Stable dry powders and emulsions containing probiotics FABP2, FABP6, MUC1 RXFP4 3365/4885RXFP3 3550/4885GLP1R 3660/4885
US-12208125-B2 Stable dry powders and emulsions containing probiotics FABP2, FABP6, MUC1 RXFP4 3365/4885RXFP3 3550/4885GLP1R 3660/4885
US-20230047790-A1 STABLE DRY POWDERS AND EMULSIONS CONTAINING PROBIOTICS FABP2, FABP6, MUC1 RXFP4 3365/4885RXFP3 3550/4885GLP1R 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.