SCHEMBL29378709

SCHEMBL29378709

C[C@H](N)C(=O)N[C@H](CC(=O)O)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.49
ENPEP Q07075 7/20 0.48
GNPAT O15228 1/20 0.47
ECE1 P42892 2/20 0.47
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
NOD1 Q9Y239 1/20 0.46
ACE P12821 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7825934 1.00 MME (0.49) MMEENPEPGNPATECE1CA2
SCHEMBL8648570 1.00 MME (0.49) MMEENPEPGNPATECE1CA2
SCHEMBL30355295 1.00 MME (0.49) MMEENPEPGNPATECE1CA2
SCHEMBL8650914 1.00 MME (0.49) MMEENPEPGNPATECE1CA2
SCHEMBL30798028 0.96 GNPAT (0.53) MMEENPEPGNPATECE1CA2
SCHEMBL30798044 0.96 GNPAT (0.53) MMEENPEPGNPATECE1CA2
SCHEMBL29384981 0.93 ENPEP (0.44) MMEENPEPGNPATECE1CA2
SCHEMBL30193555 0.91 MME (0.54) MMEENPEPGNPATECE1NOD1
SCHEMBL30193189 0.91 MME (0.54) MMEENPEPGNPATECE1NOD1
SCHEMBL26222728 0.91 GNPAT (0.46) MMEENPEPGNPATECE1NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4114417-A2 THERAPEUTIC AGENTS AND CONJUGATES THEREOF Beijing Xuanyi Pharmasciences Co., Ltd. (CN) 2023-01-11 EP claimed
CN-115427051-A Therapeutic agents and conjugates thereof 北京轩义医药科技有限公司 2022-12-02 CN claimed
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS EXELIXIS, INC. 2022-08-18 US claimed
EP-3999118-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY Immunesensor Therapeutics, Inc. (US) 2022-05-25 EP claimed
EP-3994150-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS Iconic Therapeutics, Inc. (US) 2022-05-11 EP claimed
US-12624118-B2 Trispecific binding molecules against BCMA and uses thereof NOVARTIS AG (CH) 2026-05-12 US disclosed
US-20260035473-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOFPrivate view NOVARTIS AG (CH) 2026-02-05 US disclosed
US-20260028420-A1 ANTI-TUMOR ANTIBODIES IMMUNOME INC (US) 2026-01-29 US disclosed
US-20260022193-A1 METHODS OF TREATMENT USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 ZYMEWORKS BC INC (CA) 2026-01-22 US disclosed
US-20260014265-A1 TRIPLE-PAYLOAD ANTIBODY-DRUG CONJUGATES (ADCs) ARARIS BIOTECH AG (CH) 2026-01-15 US disclosed
EP-4653017-A1 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Tyligand Bioscience (Shanghai) Limited (CN) 2025-11-26 EP disclosed
US-20250339552-A1 ANTIBODY-DRUG CONJUGATES TARGETING FOLATE RECEPTOR ALPHA AND METHODS OF USE ZYMEWORKS BC INC (CA) 2025-11-06 US disclosed
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY IMMUNESENSOR THERAPEUTICS, INC. 2022-04-07 US disclosed
EP-3976098-A1 METHODS OF USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 FOR THE TREATMENT OF BILIARY TRACT CANCERS Zymeworks Inc. (CA) 2022-04-06 EP disclosed
EP-3972993-A1 VARIANT CD58 DOMAINS AND USES THEREOF Novartis AG (CH) 2022-03-30 EP disclosed
EP-3972634-A2 TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF Novartis AG (CH) 2022-03-30 EP disclosed
EP-3972998-A1 CD19 BINDING MOLECULES AND USES THEREOF Novartis AG (CH) 2022-03-30 EP disclosed
US-20220089772-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES GO THERAPEUTICS, INC. (US) 2022-03-24 US disclosed
CN-114222752-A Anti-tissue factor antibody-drug conjugates and related methods 伊科尼克治疗公司 2022-03-22 CN disclosed
CN-114025795-A Methods of treating biliary tract cancer using bispecific antigen-binding constructs targeting HER2 酵活有限公司 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014265-A1 TRIPLE-PAYLOAD ANTIBODY-DRUG CONJUGATES (ADCs) TOP2A, TOP1, TOP2B MME 2553/4885ENPEP 883/4885GNPAT 3858/4885
US-20250339552-A1 ANTIBODY-DRUG CONJUGATES TARGETING FOLATE RECEPTOR ALPHA AND METHODS OF USE FOLR1, FOLR2, DHFR MME 4673/4885ENPEP 2089/4885GNPAT 1262/4885
US-20220105198-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY STING1, CGAS, MAVS MME 3048/4885ENPEP 1569/4885GNPAT 2911/4885
US-20260022193-A1 METHODS OF TREATMENT USING A BISPECIFIC ANTIGEN-BINDING CONSTRUCT TARGETING HER2 IGSF11, ERBB2, PDCD1LG2 MME 2116/4885ENPEP 1024/4885GNPAT 4717/4885
US-20220257789-A1 ANTI-TISSUE FACTOR ANTIBODY-DRUG CONJUGATES AND RELATED METHODS F3, F13B, TFPI MME 302/4885ENPEP 245/4885GNPAT 1327/4885
US-20260035473-A1 BINDING MOLECULES AGAINST BCMA AND USES THEREOFPrivate view BCL9, BRCA1, VCAM1 MME 3834/4885ENPEP 1840/4885GNPAT 4809/4885
US-12624118-B2 Trispecific binding molecules against BCMA and uses thereof CD2, CD40, CD22 MME 1942/4885ENPEP 1841/4885GNPAT 2214/4885
US-20220089772-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES MUC1, SIGLEC7, SIGLEC9 MME 1375/4885ENPEP 236/4885GNPAT 1776/4885
US-20260028420-A1 ANTI-TUMOR ANTIBODIES B4GALT1, ST6GAL1, GALNT3 MME 2133/4885ENPEP 234/4885GNPAT 375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.