SCHEMBL29394495

SCHEMBL29394495

[N-]=[N+]=C1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.38
KMT2A Q03164 4/20 0.38
MAPK1 P28482 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
S100A4 P26447 2/20 0.38
NPC1 O15118 2/20 0.38
MAOA P21397 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CES2 O00748 1/20 0.38
APAF1 O14727 1/20 0.38
TERT O14746 1/20 0.38
PLIN1 O60240 1/20 0.38
TDP2 O95551 1/20 0.38
S1PR4 O95977 1/20 0.38
PLA2G1B P04054 1/20 0.38
BCHE P06276 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482108 1.00 MEN1 (0.38) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8994826 0.92 SMN1; SMN2 (0.33) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8936666 0.84 MEN1 (0.60) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL3888093 0.83 ALDH1A1 (0.46) MAPK1LMNAMAPTALDH1A1L3MBTL1
SCHEMBL482129 0.82 S100A4 (0.55) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8076780 0.82 SMN1; SMN2 (0.37) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL8076772 0.82 SMN1; SMN2 (0.37) MEN1KMT2AMAPK1SMN1; SMN2LMNA
SCHEMBL10425615 0.80 GPR3 (0.41) PTPRCL3MBTL1CYP1A2GPR3
SCHEMBL10426587 0.80 S100A4 (0.52) MEN1KMT2ASMN1; SMN2S100A4NPC1
SCHEMBL8964577 0.77 S100A4 (0.48) MEN1KMT2AMAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629683-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2026-05-19 US disclosed
US-12577702-B2 Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics Plexium, Inc. (US) 2026-03-17 US disclosed
US-12030057-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2024-07-09 US disclosed
US-11884619-B2 Reagents and methods for esterification WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-01-30 US disclosed
US-20230234065-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES Plexium, Inc. 2023-07-27 US disclosed
US-20230065224-A1 OLIGONUCLEOTIDE ENCODED CHEMICAL LIBRARIES, RELATED SYSTEMS, DEVICES, AND METHODS FOR DETECTING, ANALYZING, QUANTIFYING, AND TESTING BIOLOGICS/GENETICS PLEXIUM INC (US) 2023-03-02 US disclosed
US-11577249-B2 Oligonucleotide encoded chemical libraries Plexium, Inc. (US) 2023-02-14 US disclosed
US-20220055979-A1 Reagents and Methods for Esterification WISCONSIN ALUMNI RESEARCH FOUNDATION 2022-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12629683-B2 Oligonucleotide encoded chemical libraries POLL, PCNA, POLM MEN1 3099/4885KMT2A 187/4885MAPK1 1953/4885
US-12577702-B2 Oligonucleotide encoded chemical libraries, related systems, devices, and methods for detecting, analyzing, quantifying, and testing biologics/genetics RNGTT, TNFSF11, PCNA MEN1 4122/4885KMT2A 3373/4885MAPK1 2769/4885
US-11884619-B2 Reagents and methods for esterification ADCY1, ADCY4, ADCY7 MEN1 723/4885KMT2A 2740/4885MAPK1 701/4885
US-20220055979-A1 Reagents and Methods for Esterification ADCY1, ADCY4, ADCY7 MEN1 723/4885KMT2A 2740/4885MAPK1 701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.