Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77957 | 0.82 | ALDH1A1 (0.54) | CNR2MEN1KMT2A | |
| SCHEMBL64440 | 0.80 | MEN1 (0.56) | RARBRARGCNR2MEN1KMT2A | |
| SCHEMBL3686969 | 0.80 | CNR2 (0.71) | CNR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL29057750 | 0.80 | HPGD (0.56) | CNR2MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2121314 | 0.78 | MAPT (0.54) | RARBRARGCNR2MEN1KMT2A | |
| Sulfuric Acid SCHEMBL7589189 | 0.78 | CNR2 (0.59) | CNR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28500135 | 0.77 | SRD5A2 (0.59) | KMT2ALTB4R2CA12CA1CA2 | |
| SCHEMBL5052763 | 0.76 | CNR2 (0.59) | CNR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1289403 | 0.76 | CA12 (0.70) | RARBMEN1KMT2ACA12CA1 | |
| Benzoic Acid SCHEMBL7064148 | 0.76 | SRD5A2 (0.71) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | HFC PRESTIGE SERVICE GERMINY GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11324688-B2 | Bicomponent composition | WELLA INTERNATIONAL OPERATIONS SWI (CH) | 2022-05-10 | — | — | US | disclosed |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2022-02-24 | — | — | US | disclosed |
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | HFC PRESTIGE SERVICE GERMANY GMBH (DE) | 2022-01-20 | — | — | US | disclosed |
| EP-3890683-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-10-13 | — | — | EP | disclosed |
| US-20210290519-A1 | MULTICOMPONENT SILICONE COMPOSITION | WELLA INT OPERATIONS SWITZERLAND SARL (CH) | 2021-09-23 | — | — | US | disclosed |
| US-20210290518-A1 | MULTICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2021-09-23 | — | — | US | disclosed |
| US-20210145726-A1 | BICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2021-05-20 | — | — | US | disclosed |
| EP-3817825-A1 | MULTICOMPONENT PUR COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-05-12 | — | — | EP | disclosed |
| EP-3817710-A1 | MULTICOMPONENT SILICONE COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-05-12 | — | — | EP | disclosed |
| EP-3787753-A1 | MULTICOMPONENT COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-03-10 | — | — | EP | disclosed |
| EP-3773922-A1 | BICOMPONENT COMPOSITION | HFC Prestige International Holding Switzerland S.a.r.l. (CH) | 2021-02-17 | — | — | EP | disclosed |
| WO-2020114647-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-06-11 | — | — | WO | disclosed |
| WO-2020007511-A1 | MULTICOMPONENT SILICONE COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-01-09 | — | — | WO | disclosed |
| WO-2020007510-A1 | MULTICOMPONENT PUR COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2020-01-09 | — | — | WO | disclosed |
| WO-2019192916-A1 | BICOMPONENT COMPOSITION | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2019-10-10 | — | — | WO | disclosed |
| US-20100291229-A1 | FUNGICIDAL COMPOSITIONS AND METHODS OF ENHANCING PLANTS SUCH AS TURFGRASS | SIPCAM ARGO USA, INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291229-A1 | FUNGICIDAL COMPOSITIONS AND METHODS OF ENHANCING PLANTS SUCH AS TURFGRASS | PPA1, PHOSPHO1, PFKFB1 | RARB 3112/4885RARG 1631/4885CNR2 4462/4885 |
| US-20220016017-A1 | COLOR COATINGS WITH DOWNSTREAM FEATURES | KRT18, ITGA5, FLNA | RARB 64/4885RARG 44/4885CNR2 2418/4885 |
| US-20230310300-A1 | HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER | KRT18, MKI67, IK | RARB 463/4885RARG 541/4885CNR2 4532/4885 |
| US-20210290519-A1 | MULTICOMPONENT SILICONE COMPOSITION | CUTA, CD99, PLOD3 | RARB 498/4885RARG 647/4885CNR2 4824/4885 |
| US-20220054392-A1 | MULTICOMPONENT IN SITU COLORATION COMPOSITION | KRT18, PRKDC, VIM | RARB 2777/4885RARG 2930/4885CNR2 4453/4885 |
| US-11324688-B2 | Bicomponent composition | KRT18, EXOSC10, EXOSC9 | RARB 225/4885RARG 206/4885CNR2 4764/4885 |
| US-20210290518-A1 | MULTICOMPONENT COMPOSITION | KRT18, INCENP, IK | RARB 38/4885RARG 33/4885CNR2 3756/4885 |
| US-20210145726-A1 | BICOMPONENT COMPOSITION | KRT18, EXOSC10, EXOSC9 | RARB 225/4885RARG 206/4885CNR2 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.