SCHEMBL29445631

SCHEMBL29445631

O=C[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 3/20 0.45
▸ MDM4 O15151 2/20 0.45
▸ TP53 P04637 2/20 0.45
▸ SIRT2 Q8IXJ6 12/20 0.43
▸ NMBR P28336 1/20 0.40
▸ MDM2 Q00987 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1737899 0.87 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL12994493 0.87 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL29368020 0.87 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL30433831 0.87 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL13227674 0.87 MDM4 (0.54) MDM4TP53SIRT2MDM2
SCHEMBL30468161 0.86 SIRT2 (0.55) MDM4TP53SIRT2NMBRMDM2
SCHEMBL18758112 0.84 CASP3 (0.46) CASP3MDM4TP53MDM2
SCHEMBL30385679 0.84 MDM4 (0.49) MDM4TP53SIRT2NMBRMDM2
SCHEMBL28625947 0.83 MDM2 (0.52) MDM4TP53SIRT2MDM2
SCHEMBL30434660 0.83 MDM2 (0.52) MDM4TP53SIRT2MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025264177-A1 METHOD FOR CLEAVING PROTECTING GROUPS AND ORGANIC COMPOUNDS FROM SUPPORTS POLYPEPTIDE LABORATORIES HOLDING (PPL) AB (SE) 2025-12-26 — — WO disclosed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 — — US disclosed
CN-119841893-A Preparation method of polypeptide with anti-inflammatory effect 兰树化妆品股份有限公司 2025-04-18 — — CN disclosed
EP-4532513-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2025-04-09 — — EP disclosed
CN-119451974-A Cyclic peptides having antibacterial activity against Multiple Drug Resistant (MDR) pathogens 巴塞罗那全球健康研究所私人基金会 2025-02-14 — — CN disclosed
CN-118987168-A Multifunctional active peptide and application thereof 山东第二医科大学 2024-11-22 — — CN disclosed
US-20240294573-A1 CONSTRAINED PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-09-05 — — US disclosed
US-20240083943-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2024-03-14 — — US disclosed
WO-2023227771-A1 CYCLIC PEPTIDES WITH ANTIBACTERIAL ACTIVITY AGAINST MULTIDRUG RESISTANT (MDR) PATHOGENS Fundación Privada Instituto De Salud Global Barcelona (ES) 2023-11-30 — — WO disclosed
EP-4271480-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2023-11-08 — — EP disclosed
US-20220306708-A1 BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2022-09-29 — — US disclosed
US-11440939-B2 Anticancer peptides IDP DISCOVERY PHARMA, S.L. (ES) 2022-09-13 — — US disclosed
EP-4039698-A1 PEPTIDES WITH ANTI-CANCER ACTIVITY IDP Discovery Pharma, S.L. (ES) 2022-08-10 — — EP disclosed
WO-2022144401-A1 VEGF-REGULATING PEPTIDES IDP DISCOVERY PHARMA, S.L. (ES) 2022-07-07 — — WO disclosed
EP-4023295-A1 VEGF-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-07-06 — — EP disclosed
EP-4007563-A1 MELANOCYTE-REGULATING PEPTIDES IDP Discovery Pharma, S.L. (ES) 2022-06-08 — — EP disclosed
US-11352395-B2 Anticancer peptides IDP DISCOVERY PHARMA, S.L. (ES) 2022-06-07 — — US disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 — — EP disclosed
CN-113717254-B Antibacterial peptide and application thereof 中山大学附属口腔医院 2022-03-22 — — CN disclosed
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 CASP3 4704/4885MDM4 450/4885TP53 628/4885
US-11440939-B2 Anticancer peptides NGLY1, SLC1A5, SSTR5 CASP3 1352/4885MDM4 377/4885TP53 37/4885
US-11279734-B2 Solution-phase affinity selection of inhibitors from combinatorial peptide libraries TP53, MDM2, MDM4 CASP3 2615/4885MDM4 3/4885TP53 1/4885
US-20240294573-A1 CONSTRAINED PEPTIDES IAPP, NGLY1, VIP CASP3 1870/4885MDM4 2200/4885TP53 493/4885
US-11352395-B2 Anticancer peptides PNISR, NGLY1, SLC1A5 CASP3 2512/4885MDM4 265/4885TP53 124/4885
US-20220306708-A1 BIFUNCTIONAL STAPLED POLYPEPTIDES AND USES THEREOF TIMCC, CCL2, SGTA CASP3 2347/4885MDM4 2168/4885TP53 258/4885
US-20240083943-A1 VEGF-REGULATING PEPTIDES VEGFA, FLT4, FLT1 CASP3 3795/4885MDM4 662/4885TP53 294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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