SCHEMBL29449769

SCHEMBL29449769

COc1ccc(Cn2c(NCCN=C(N)N)nc(=O)n(Cc3ccc(Br)cc3)c2=O)cc1

nearest known ligand 0.90

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PROKR1 Q8TCW9 20/20 0.90
PROKR2 Q8NFJ6 1/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1750900 0.77 PROKR1 (0.74) PROKR1PROKR2
SCHEMBL326251 0.77 PROKR1 (1.00) PROKR1PROKR2
SCHEMBL8279989 0.76 PROKR1 (0.74) PROKR1PROKR2
SCHEMBL5434959 0.76 PROKR1 (0.73) PROKR1PROKR2
SCHEMBL8280045 0.76 PROKR1 (0.66) PROKR1PROKR2
SCHEMBL8280035 0.76 PROKR1 (0.73) PROKR1PROKR2
SCHEMBL1752180 0.76 PROKR1 (0.77) PROKR1PROKR2
SCHEMBL326449 0.76 PROKR1 (0.82) PROKR1PROKR2
SCHEMBL8528608 0.76 PROKR1 (0.74) PROKR1PROKR2
SCHEMBL5960121 0.75 PROKR1 (0.73) PROKR1PROKR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119307137-A Household multifunctional water-based strippable antiviral coating composition, preparation method and application thereof 立邦涂料(中国)有限公司 2025-01-14 CN claimed
CN-118240432-A Blue light-resistant photochromic paint and preparation method thereof 广东三和化工科技有限公司 2024-06-25 CN claimed
CN-113025122-B Water-based lasting erasable ink and preparation method thereof 上海纳诺微新材料科技有限公司 2023-02-03 CN claimed
CN-122071576-A Polycarbonate polyol composition, adhesive composition, aqueous polyurethane, aqueous dispersion composition, polyurethane for synthetic leather, and synthetic leather 旭化成株式会社 2026-05-22 CN disclosed
US-12581628-B2 Electromagnetic interference suppressing material KYOCERA CORPORATION (JP) 2026-03-17 US disclosed
CN-120118192-A Precursor trispecific antibody constructs and methods of use thereof 免疫里森公司 2025-06-10 CN disclosed
WO-2025097043-A1 ANTIBODIES FOR TARGETING PSMA AND CD28 AND USES THEREOF Janux Therapeutics, Inc. (US) 2025-05-08 WO disclosed
CN-115197409-B Polycarbonate diol and process for producing the same 旭化成株式会社 2025-04-15 CN disclosed
US-20250115590-A1 MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF FORESEE PHARMACEUTICALS USA, INC. 2025-04-10 US disclosed
CN-113748184-B Boron-containing cyclic light-emitting compound and color conversion film containing same 日东电工株式会社 2025-04-04 CN disclosed
CN-113811546-B Precursor trispecific antibody constructs and methods of use thereof 免疫里森公司 2025-03-11 CN disclosed
CN-115717044-A Photocuring hot melt adhesive for leather and preparation process thereof 杭州仁和热熔胶有限公司 2023-02-28 CN disclosed
CN-113025122-B Water-based lasting erasable ink and preparation method thereof 上海纳诺微新材料科技有限公司 2023-02-03 CN disclosed
CN-115650634-A Plant-mixed cold-recycling mixture and road surface construction method 山东建筑大学 2023-01-31 CN disclosed
CN-112976840-B Heat transfer printing film for vehicle license plate and preparation method thereof 焦作卓立膜材料股份有限公司 2022-12-02 CN disclosed
CN-115197409-A Polycarbonate diol and method for producing same 旭化成株式会社 2022-10-18 CN disclosed
CN-114983851-A Hair loss preventing and hair nourishing composition and hair washing and caring preparation thereof 洋妆源(天津)网络科技有限公司 2022-09-02 CN disclosed
CN-114865092-A Nonaqueous lithium ion battery electrolyte and lithium ion battery 上海大学 2022-08-05 CN disclosed
US-20220216411-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME NITTO DENKO CORP (JP) 2022-07-07 US disclosed
CN-114181604-A Water-based strippable paint and preparation method thereof 江苏奥斯佳材料科技股份有限公司 2022-03-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216411-A1 BORON-CONTAINING CYCLIC EMISSIVE COMPOUNDS AND COLOR CONVERSION FILM CONTAINING THE SAME BLVRB, CLTB, CRY1 PROKR1 4869/4885PROKR2 4873/4885
US-12581628-B2 Electromagnetic interference suppressing material GJA1, GJB2, EXOSC10 PROKR1 3749/4885PROKR2 3809/4885
US-20250115590-A1 MATRIX METALLOPROTEINASE (MMP) INHIBITORS AND METHODS OF USE THEREOF MMP12, MMP1, MMP11 PROKR1 981/4885PROKR2 1168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.