Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 11/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.97 |
| ▸ | USP2 | O75604 | 2/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | LTA | P01374 | 2/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.97 |
| ▸ | HPGD | P15428 | 2/20 | 0.97 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.97 |
| ▸ | RAD1 | O60671 | 1/20 | 0.68 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903158 | 0.98 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL439382 | 0.98 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29523045 | 0.98 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL31196489 | 0.98 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL30889118 | 0.84 | RAD51 (0.75) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29627175 | 0.83 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2415107 | 0.83 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2333709 | 0.83 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29350628 | 0.81 | P2RY6 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29351286 | 0.81 | P2RY6 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024210479-A1 | COMPOSITION CONTAINING LOW-MOLECULAR-WEIGHT COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | 주식회사 에스씨엘테라퓨틱스 | 2024-10-10 | — | — | WO | claimed |
| US-12287336-B2 | Protein for rapid, efficient capture of antigens | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-04-29 | — | — | US | disclosed |
| WO-2024210479-A1 | COMPOSITION CONTAINING LOW-MOLECULAR-WEIGHT COMPOUND AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | 주식회사 에스씨엘테라퓨틱스 | 2024-10-10 | — | — | WO | disclosed |
| US-20240325517-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | INIMMUNE CORPORATION | 2024-10-03 | — | — | US | disclosed |
| EP-4133263-B1 | CAPILLARY GEL ELECTROPHORESIS AND ITS USE WITH COMPLEX BIOLOGICAL MOLECULES | ARES TRADING SA (CH) | 2024-05-22 | — | — | EP | disclosed |
| US-20230408515-A1 | ENGINEERED PROTEIN FOR RAPID, EFFICIENT CAPTURE OF PATHOGEN-SPECIFIC ANTIBODIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-12-21 | — | — | US | disclosed |
| US-20230305002-A1 | PROTEIN FOR RAPID, EFFICIENT CAPTURE OF ANTIGENS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-09-28 | — | — | US | disclosed |
| US-11740236-B2 | Protein for rapid, efficient capture of antigens | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-08-29 | — | — | US | disclosed |
| EP-4213943-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | The University Of Montana (US) | 2023-07-26 | — | — | EP | disclosed |
| US-20230152275-A1 | CAPILLARY GEL ELECTROPHORESIS AND ITS USE WITH COMPLEX BIOLOGICAL MOLECULES | ARES TRADING S.A. (CH) | 2023-05-18 | — | — | US | disclosed |
| US-11598769-B2 | Oligomerized protein-polymer conjugates | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-03-07 | — | — | US | disclosed |
| EP-4133263-A1 | CAPILLARY GEL ELECTROPHORESIS AND ITS USE WITH COMPLEX BIOLOGICAL MOLECULES | Ares Trading S.A. (CH) | 2023-02-15 | — | — | EP | disclosed |
| CN-115398219-A | Capillary gel electrophoresis and its use in complex biomolecules | 阿瑞斯贸易股份公司 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022103797-A1 | ENGINEERED PROTEIN FOR RAPID, EFFICIENT CAPTURE OF PATHOGEN-SPECIFIC ANTIBODIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022103793-A1 | ENGINEERED PROTEINS THAT BIND THE SARS-COV-2 NUCLEOCAPSID PROTEIN | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-05-19 | — | — | WO | disclosed |
| WO-2022060905-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | THE UNIVERSITY OF MONTANA (US) | 2022-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230305002-A1 | PROTEIN FOR RAPID, EFFICIENT CAPTURE OF ANTIGENS | CD2BP2, HSPBP1, CD74 | RAD51 2050/4885KDM4E 4276/4885USP2 1042/4885 |
| US-12287336-B2 | Protein for rapid, efficient capture of antigens | CD2BP2, HSPBP1, CD74 | RAD51 2050/4885KDM4E 4276/4885USP2 1042/4885 |
| US-20230408515-A1 | ENGINEERED PROTEIN FOR RAPID, EFFICIENT CAPTURE OF PATHOGEN-SPECIFIC ANTIBODIES | SARS1, CD2BP2, ACE2 | RAD51 1971/4885KDM4E 3927/4885USP2 745/4885 |
| US-20240325517-A1 | COMPOSITIONS AND METHODS TARGETING FILAMENTOUS BACTERIOPHAGE | TLR8, TLR3, TLR4 | RAD51 2125/4885KDM4E 1955/4885USP2 2055/4885 |
| US-11740236-B2 | Protein for rapid, efficient capture of antigens | CD2BP2, HSPBP1, CD74 | RAD51 2050/4885KDM4E 4276/4885USP2 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.