Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 known ✓ | Q15077 | 1/20 | 0.70 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 11/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | LTA | P01374 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | P2RX3 | P56373 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | RAD1 | O60671 | 1/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29523045 | 1.00 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL7903158 | 1.00 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL31196489 | 1.00 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| Water SCHEMBL29459684 | 0.98 | RAD51 (0.97) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL30889118 | 0.86 | RAD51 (0.75) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2333709 | 0.84 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29627175 | 0.84 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL2415107 | 0.84 | RAD51 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29350628 | 0.83 | P2RY6 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA | |
| SCHEMBL29351286 | 0.83 | P2RY6 (1.00) | RAD51KDM4EUSP2ALDH1A1LTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934110-B1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIV GENT (BE) | 2018-08-01 | — | — | EP | claimed |
| US-9485983-B2 | Use of connexin channel inhibitors to protect grafts | UNIVERSITEIT GENT (BE) | 2016-11-08 | — | — | US | claimed |
| US-20150313208-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2015-11-05 | — | — | US | claimed |
| EP-2934110-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | Universiteit Gent (BE) | 2015-10-28 | — | — | EP | claimed |
| WO-2014095468-A1 | USE OF CONNEXIN CHANNEL INHIBITORS TO PROTECT GRAFTS | UNIVERSITEIT GENT (BE) | 2014-06-26 | — | — | WO | claimed |
| US-20110189310-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2011-08-04 | — | — | US | claimed |
| WO-2010042728-A1 | SMALL MOLECULE MODULATORS OF PRONGF UPTAKE | CORNELL UNIVERSITY (US) | 2010-04-15 | — | — | WO | claimed |
| US-7238794-B2 | Organic conductor | FUJI XEROX CO., LTD. (JP) | 2007-07-03 | — | — | US | claimed |
| US-20030170692-A1 | Organic conductor | FUJI XEROX CO., LTD. (JP) | 2003-09-11 | — | — | US | claimed |
| EP-1324352-A2 | Organic conductor | FUJI XEROX CO., LTD. (JP) | 2003-07-02 | — | — | EP | claimed |
| US-12427120-B2 | Compositions comprising guaifenesin and flavour compounds containing an isovanillyl group | SYMRISE AG (DE) | 2025-09-30 | — | — | US | disclosed |
| US-20240382417-A1 | Compositions Comprising Guaifenesin and Eriodictyol | SYMRISE AG (DE) | 2024-11-21 | — | — | US | disclosed |
| US-20240233860-A1 | METHOD FOR MODELING CYCLIC 3D EPITOPES TO BE USED IN THE DEVELOPMENT OF VACCINES | SYNTHETIC VACCINES LTD (GB) | 2024-07-11 | — | — | US | disclosed |
| EP-4133263-B1 | CAPILLARY GEL ELECTROPHORESIS AND ITS USE WITH COMPLEX BIOLOGICAL MOLECULES | ARES TRADING SA (CH) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024094986-A1 | METHOD | OXFORD NANOPORE TECHNOLOGIES PLC (GB) | 2024-05-10 | — | — | WO | disclosed |
| EP-0547142-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | EPOCH PHARMACEUTICALS, INC. (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5166063-A | IMMOBOLIZATION OF BIOMOLECULES BY ENHANCED ELECTROPHORETIC PRECIPITATION | ELI LILLY AND COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
| WO-1992003464-A1 | SOLID SUPPORT SYNTHESIS OF 3'-TAILED OLIGONUCLEOTIDES VIA A LINKING MOLECULE | MICROPROBE CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |
| EP-0463859-A2 | Immobilization of biomolecules by enhanced electrophoretic precipitation | ELI LILLY AND COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| US-5011644-A | Process for producing gel fiber | CANON KABUSHIKI KAISHA (JP) | 1991-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240382417-A1 | Compositions Comprising Guaifenesin and Eriodictyol | ERLIN1, TAS2R38, TAS2R39 | P2RY6 1369/4885CA1 2179/4885CA2 1149/4885 |
| US-12427120-B2 | Compositions comprising guaifenesin and flavour compounds containing an isovanillyl group | TAS1R1, TAS2R40, TAS2R5 | P2RY6 348/4885CA1 3691/4885CA2 2768/4885 |
| US-20030170692-A1 | Organic conductor | DNMT1, DNMT3A, POLN | P2RY6 1326/4885CA1 1168/4885CA2 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.