SCHEMBL29461982

SCHEMBL29461982

CC(C)[C@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 14/20 0.52
▸ NPY1R P25929 8/20 0.52
▸ NPY2R P49146 6/20 0.52
▸ NPY5R Q15761 6/20 0.52
▸ IL23R Q5VWK5 3/20 0.50
▸ C5AR1 P21730 1/20 0.50
▸ TFPI P10646 1/20 0.48
▸ KISS1R Q969F8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31680267 0.93 NPY4R (0.58) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL29868927 0.92 NPY4R (0.57) NPY4RNPY1RNPY2RNPY5RIL23R
SCHEMBL30463393 0.89 NPY4R (0.52) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30540722 0.88 NPY4R (0.63) NPY4RNPY1RNPY2RNPY5RC5AR1
SCHEMBL29461967 0.87 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29540539 0.87 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29936549 0.86 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30427476 0.86 NPY4R (0.61) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30309227 0.85 NPY4R (0.67) NPY4RNPY1RNPY2RNPY5R
SCHEMBL29904555 0.85 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 — — EP disclosed
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 — — US disclosed
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 — — US disclosed
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING STEALTH BIOTHERAPEUTICS INC. (US) 2025-10-16 — — US disclosed
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 — — US disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 — — US disclosed
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-21 — — US disclosed
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-14 — — US disclosed
EP-4596049-A2 PEPTIDE FOR USE IN PREVENTING OR TREATING MACULAR DEGENERATION Stealth BioTherapeutics Inc. (US) 2025-08-06 — — EP disclosed
US-12337023-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2025-06-24 — — US disclosed
EP-4085920-A1 METHODS FOR THE TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY Stealth BioTherapeutics Inc. (US) 2022-11-09 — — EP disclosed
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-22 — — US disclosed
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-08 — — US disclosed
US-11420998-B2 Aromatic-cationic peptides and methods for using same STEALTH BIOTHERAPEUTICS INC. (US) 2022-08-23 — — US disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 — — US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 — — US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 — — EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 — — EP disclosed
US-11312993-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2022-04-26 — — US disclosed
US-11266709-B2 Methods for the regulation of matrix metalloproteinase expression STEALTH BIOTHERAPEUTICS INC. (US) 2022-03-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME ARG2, ARGLU1, BCAT1 NPY4R 2600/4885NPY1R 872/4885NPY2R 1761/4885
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH TNNI3, TNNT2, FABP3 NPY4R 2454/4885NPY1R 1553/4885NPY2R 2489/4885
US-12337023-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY2R 820/4885
US-20220296672-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT NEUROPATHY NGF, GAP43, PRPH NPY4R 520/4885NPY1R 328/4885NPY2R 395/4885
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 NPY4R 350/4885NPY1R 209/4885NPY2R 317/4885
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING ARG2, TNNT2, MYLK2 NPY4R 700/4885NPY1R 913/4885NPY2R 313/4885
US-11420998-B2 Aromatic-cationic peptides and methods for using same ARG2, ARGLU1, ARG1 NPY4R 824/4885NPY1R 523/4885NPY2R 730/4885
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS ARG2, MTPN, TNNT2 NPY4R 3734/4885NPY1R 3368/4885NPY2R 4078/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY2R 820/4885
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 NPY4R 350/4885NPY1R 209/4885NPY2R 317/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB NPY4R 4783/4885NPY1R 4818/4885NPY2R 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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