Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154884 | 1.00 | LMNA (0.53) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL12422620 | 1.00 | LMNA (0.53) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL9204113 | 1.00 | LMNA (0.53) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL3089641 | 1.00 | LMNA (0.53) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL7155404 | 1.00 | LMNA (0.53) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16153910 | 0.92 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL14411837 | 0.92 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL16153889 | 0.92 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL15698703 | 0.92 | LMNA (0.58) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL17472887 | 0.90 | TDP1 (0.60) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | claimed |
| US-12570676-B2 | Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2026-03-10 | — | — | US | disclosed |
| EP-4430031-A1 | HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES AND METAL-FREE CLICK REACTIONS WITH THESE HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-09-18 | — | — | EP | disclosed |
| US-20240300900-A1 | HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES AND METAL-FREE CLICK REACTIONS WITH THESE HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2024-09-12 | — | — | US | disclosed |
| CN-118234709-A | Hydrophilic azadibenzocyclooctyne derivatives and metal-free click reactions with these hydrophilic azadibenzocyclooctyne derivatives | 豪夫迈·罗氏有限公司 | 2024-06-21 | — | — | CN | disclosed |
| EP-4324928-A1 | SYNTHETIC REAGENTS FOR ENZYME-CATALYSED ALKYLATION | Universität Basel (CH) | 2024-02-21 | — | — | EP | disclosed |
| CN-110709523-B | Sequencing reaction method using tagged nucleosides obtained via PICTET SPENGLER reaction | 豪夫迈·罗氏有限公司 | 2023-07-11 | — | — | CN | disclosed |
| WO-2023083895-A1 | HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES AND METAL-FREE CLICK REACTIONS WITH THESE HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-05-19 | — | — | WO | disclosed |
| US-11618790-B2 | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | disclosed |
| EP-3504155-B1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | ROCHE DIAGNOSTICS GMBH (DE) | 2023-03-08 | — | — | EP | disclosed |
| US-20220169664-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESS FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2022-06-02 | — | — | US | disclosed |
| US-11293060-B2 | Method for labeling of aldehyde containing target molecules | Roche Sequencing Solutions, Inc. (US) | 2022-04-05 | — | — | US | disclosed |
| US-11267827-B2 | Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570676-B2 | Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods | SELP, SELPLG, SELE | LMNA 574/4885L3MBTL1 3011/4885TDP1 3389/4885 |
| US-11267827-B2 | Multifunctionalized silicon nanoparticles, process for their preparation and uses thereof in electrochemiluminescence based detection methods | SELE, SIK1, SIK2 | LMNA 393/4885L3MBTL1 3077/4885TDP1 1746/4885 |
| US-11618790-B2 | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery | PNKP, RNASE1, DCLRE1B | LMNA 732/4885L3MBTL1 392/4885TDP1 236/4885 |
| US-20240300900-A1 | HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES AND METAL-FREE CLICK REACTIONS WITH THESE HYDROPHILIC AZADIBENZOCYCLOOCTYNE DERIVATIVES | HLCS, AOC1, AZI2 | LMNA 1601/4885L3MBTL1 3820/4885TDP1 4745/4885 |
| US-20220169664-A1 | MULTIFUNCTIONALIZED SILICON NANOPARTICLES, PROCESS FOR THEIR PREPARATION AND USES THEREOF IN ELECTROCHEMILUMINESCENCE BASED DETECTION METHODS | SELE, SIK1, SIK2 | LMNA 393/4885L3MBTL1 3077/4885TDP1 1746/4885 |
| US-11293060-B2 | Method for labeling of aldehyde containing target molecules | NUDT1, RNGTT, DERA | LMNA 2017/4885L3MBTL1 991/4885TDP1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.