Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22574481 | 0.97 | CA1 (0.52) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL29402870 | 0.85 | ALDH1A1 (0.51) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL10704337 | 0.85 | ALDH1A1 (0.51) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL22574489 | 0.84 | ALDH1A1 (0.50) | CA1CA2CA4CA7KDM4E | |
| Potassium Ion SCHEMBL6555671 | 0.79 | CA1 (0.71) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL11132359 | 0.77 | ALDH1A1 (0.51) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL7074698 | 0.75 | CA1 (0.71) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL2913783 | 0.75 | POLB (0.61) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL2904641 | 0.74 | KMT2A (0.55) | CA1CA2CA4CA7KDM4E | |
| SCHEMBL2907649 | 0.74 | MEN1 (0.55) | CA1CA2CA4CA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555091-B2 | Composition with reduced aldehyde emission | HUNTSMAN INTERNATIONAL LLC (US) | 2023-01-17 | — | — | US | disclosed |
| CN-111801365-B | Compositions with reduced aldehyde emissions | 亨茨曼国际有限公司 | 2022-03-29 | — | — | CN | disclosed |