Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 6/20 | 0.71 |
| ▸ | CA2 known ✓ | P00918 | 6/20 | 0.71 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.71 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL6555671 | 0.97 | CA1 (0.71) | CA1CA2CA7CA4MAPT | |
| SCHEMBL13306091 | 0.86 | CA1 (0.75) | CA1CA2CA7CA4MAPT | |
| SCHEMBL3906878 | 0.84 | ATM (0.74) | CA1CA2CA7CA4MAPT | |
| SCHEMBL2220428 | 0.84 | CA1 (0.73) | CA1CA2CA7CA4MAPT | |
| SCHEMBL593172 | 0.83 | MAPT (0.74) | CA1CA2CA7CA4MAPT | |
| Potassium SCHEMBL29819348 | 0.83 | CA1 (0.71) | CA1CA2CA7CA4MAPT | |
| SCHEMBL7130773 | 0.83 | CA1 (1.00) | CA1CA2CA7CA4MAPT | |
| SCHEMBL7074703 | 0.83 | CA1 (0.71) | CA1CA2CA7CA4MAPT | |
| SCHEMBL6555677 | 0.83 | CA1 (0.71) | CA1CA2CA7CA4MAPT | |
| SCHEMBL8389551 | 0.82 | CA1 (0.67) | CA1CA2CA7CA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997774-B | Method for producing organic cobalt complex | 金华双宏化工有限公司 | 2020-06-26 | — | — | CN | disclosed |
| EP-1146088-B1 | Method of producing disazo pigment | TOYO INK MFG CO (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-20010041793-A1 | Method of producing disazo pigment | TOYO INK MFG. CO., LTD. (JP) | 2001-11-15 | — | — | US | disclosed |
| EP-1146088-A1 | Method of producing disazo pigment | Toyo Ink Manufacturing Co. Ltd. (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-6303762-B1 | COUPLING A TETRAZO BENZIDINES AND A MIXTURE OF N-PHENYLACETOACETAMIDES | TOYO INK MFG. CO., LTD. (JP) | 2001-10-16 | — | — | US | disclosed |