7Z-3,4,4'-Trimethoxystilbene

7Z-3,4,4'-Trimethoxystilbene

SCHEMBL2948082

COc1ccc(/C=C/c2ccc(OC)c(OC)c2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 2/20 1.00
TUBB P07437 2/20 1.00
TUBA3C P0DPH7 2/20 1.00
TUBA1B P68363 2/20 1.00
TUBA4A P68366 2/20 1.00
TUBB4B P68371 2/20 1.00
TUBB3 Q13509 2/20 1.00
TUBB2A Q13885 2/20 1.00
TUBB8 Q3ZCM7 2/20 1.00
TUBA3E Q6PEY2 2/20 1.00
TUBA1A Q71U36 2/20 1.00
TUBA1C Q9BQE3 2/20 1.00
TUBB6 Q9BUF5 2/20 1.00
TUBB2B Q9BVA1 2/20 1.00
TUBB1 Q9H4B7 2/20 1.00
CYP1A1 P04798 8/20 0.76
CYP1B1 Q16678 7/20 0.76
NQO2 P16083 4/20 0.76
TTR P02766 1/20 0.76
ABCG2 Q9UNQ0 1/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7Z-3,4,4'-Trimethoxystilbene SCHEMBL9188558 1.00 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
7Z-3,4,4'-Trimethoxystilbene SCHEMBL2948087 1.00 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9173364 0.92 CYP1A1 (0.84) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9173377 0.92 CYP1A1 (0.84) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9586847 0.89 CYP1A1 (0.80) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL9431599 0.89 CYP1A1 (0.80) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
(E)-3,4,3',5'-Tetramethoxystilbene SCHEMBL1394570 0.86 CYP1A1 (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL3750347 0.86 CYP1A1 (0.93) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL15785978 0.86 CYP1A1 (0.93) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
(E)-3,4,3',5'-Tetramethoxystilbene SCHEMBL1394568 0.86 CYP1A1 (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3280402-B1 TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING BIOMENDICS LLC (US) 2024-06-05 EP disclosed
US-11786481-B2 Formulation and process for modulating wound healing BioMendics, LLC (US) 2023-10-17 US disclosed
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
US-11318079-B2 Polyhydroxylated (1-phenyl-2-phenyl) ethylene derivatives as an anti-ageing and photoprotective agent L'OREAL (FR) 2022-05-03 US disclosed
US-11229660-B2 Glycan therapeutics and method of treating conditions associated with TMAO KALEIDO BIOSCIENCES, INC. (US) 2022-01-25 US disclosed
US-20210228501-A1 Formulation and Process for Modulating Wound Healing BioMendics, LLC (US) 2021-07-29 US disclosed
US-20210137956-A1 GLYCAN COMPOSITIONS AND USES THEREOF HERCULES CAPITAL, INC. 2021-05-13 US disclosed
US-20210113596-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2021-04-22 US disclosed
US-10881676-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2021-01-05 US disclosed
US-10702542-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2020-07-07 US disclosed
WO-2015085143-A2 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM (US) 2015-06-11 WO disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS STC.UNM (US) 2013-07-11 US disclosed
US-7759527-B2 Microwave induced one pot process for the preparation of arylethenes COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2010-07-20 US disclosed
US-20080045752-A1 Microwave Induced One Pot Process For The Preparation Of Arylethenes COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2008-02-21 US disclosed
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents REGENTS OF THE UNIVERSITY OF NEW MEXICO 2007-10-25 US disclosed
WO-2007110881-A1 A MICROWAVE INDUCED ONE POT PROCESS FOR THE PREPARATION OF ARYLETHENES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-10-04 WO disclosed
US-5430062-A Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-07-04 US disclosed
EP-0641301-A1 STILBENE DERIVATIVES AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-03-08 EP disclosed
WO-1993023357-A1 STILBENE DERIVATIVES AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080045752-A1 Microwave Induced One Pot Process For The Preparation Of Arylethenes TET2, HCN4, KDM4E TUBB4A 1651/4885TUBB 1381/4885TUBA3C 2163/4885
US-11786481-B2 Formulation and process for modulating wound healing SQSTM1, ATG7, TFEB TUBB4A 1105/4885TUBB 488/4885TUBA3C 1552/4885
US-11318079-B2 Polyhydroxylated (1-phenyl-2-phenyl) ethylene derivatives as an anti-ageing and photoprotective agent KRT18, GLA, CUTA TUBB4A 591/4885TUBB 499/4885TUBA3C 1174/4885
US-20210228501-A1 Formulation and Process for Modulating Wound Healing ATG7, SQSTM1, ATF4 TUBB4A 1300/4885TUBB 594/4885TUBA3C 1483/4885
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents TGFB1, VHL, TMSB10 TUBB4A 144/4885TUBB 58/4885TUBA3C 663/4885
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS PSEN1, TERT, PSEN2 TUBB4A 271/4885TUBB 196/4885TUBA3C 779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.