SCHEMBL2948443

SCHEMBL2948443

Fc1cc(Cl)cc(Br)c1I

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ERN1 O75460 1/20 0.32
TSHR P16473 1/20 0.32
AHR P35869 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12478321 0.82 TSHR (0.41) TSHR
SCHEMBL23648094 0.82 TSHR (0.41) ERN1TSHRAHR
SCHEMBL29363756 0.75 PDK2 (0.37) NPC1RAB9AHPGDSMN1; SMN2ERN1
SCHEMBL28901856 0.75 ALDH1A1 (0.41) HPGDSMN1; SMN2ERN1TSHRAHR
SCHEMBL29429741 0.75 TSHR (0.35) NPC1RAB9AHPGDSMN1; SMN2ERN1
SCHEMBL29363049 0.75 ALDH1A1 (0.41) HPGDSMN1; SMN2ERN1TSHRAHR
SCHEMBL29920955 0.75 MAPT (0.37) SMN1; SMN2
SCHEMBL263907 0.75 PDK2 (0.37) NPC1RAB9AHPGDSMN1; SMN2ERN1
SCHEMBL22165559 0.75 TSHR (0.35) NPC1RAB9AHPGDSMN1; SMN2ERN1
SCHEMBL29948146 0.75 AKR1B1 (0.36) NPC1RAB9AHPGDSMN1; SMN2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2822941-A1 BENZODIOXANES IN COMBINATION WITH OTHER ACTIVES FOR INHIBITING LEUKOTRIENE PRODUCTION Boehringer Ingelheim International GmbH (DE) 2015-01-14 EP claimed
WO-2013131901-A1 BENZODIOXANES IN COMBINATION WITH OTHER ACTIVES FOR INHIBITING LEUKOTRIENE PRODUCTION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-09-12 WO claimed
CN-118084840-B Organic compound, organic electroluminescent device and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL Co.,Ltd. (CN) 2026-05-26 CN disclosed
US-20260059997-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-26 US disclosed
US-12312342-B2 Compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2025-05-27 US disclosed
CN-114096535-B Heterocyclic compound, organic light-emitting element, composition for use in the same, and method for producing the same LT素材株式会社 2025-03-07 CN disclosed
CN-115551838-B Novel compound and organic light emitting device using the same 株式会社LG化学 2024-11-26 CN disclosed
CN-115785077-B Compound for organic photoelectric device, composition for organic photoelectric device, and display device 三星SDI株式会社 2024-11-22 CN disclosed
US-12108661-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-10-01 US disclosed
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode LT MATERIALS CO., LTD. (KR) 2024-06-25 US disclosed
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 WO disclosed
WO-2020122576-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, METHOD FOR MANUFACTURING SAME, AND COMPOSITION FOR ORGANIC MATERIAL LAYER 엘티소재주식회사 2020-06-18 WO disclosed
EP-3087155-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI Albemarle Corporation (US) 2016-11-02 EP disclosed
US-20160289527-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI ALBEMARLE CORP (US) 2016-10-06 US disclosed
WO-2015100004-A1 CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI ALBEMARLE CORPORATION (US) 2015-07-02 WO disclosed
US-9051311-B2 Sulfamide sodium channel inhibitors AMGEN INC. (US) 2015-06-09 US disclosed
WO-2013134518-A1 SULFAMIDE SODIUM CHANNEL INHIBITORS AMGEN INC. (US) 2013-09-12 WO disclosed
EP-2396301-A2 SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS Jerini AG (DE) 2011-12-21 EP disclosed
WO-2010091876-A2 SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS JERINI AG (DE) 2010-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12018022-B2 Heterocyclic compound, organic light emitting diode comprising same, composition for organic layer of organic light emitting diode, and method for manufacturing organic light emitting diode ODC1, AOX1, CYP1B1 NPC1 1924/4885RAB9A 3450/4885HPGD 410/4885
US-12108661-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof PIEZO1, LEF1, ELP1 NPC1 2510/4885RAB9A 3227/4885HPGD 4431/4885
US-12312342-B2 Compound and organic light emitting device comprising same CRY1, CRY2, PER2 NPC1 1073/4885RAB9A 2219/4885HPGD 2653/4885
US-20260059997-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRB, GLRA1 NPC1 2509/4885RAB9A 1475/4885HPGD 4423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.