SCHEMBL294848

SCHEMBL294848

CCCCCCCCOc1[c]cc(C(C)(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.39
NR5A1 Q13285 1/20 0.38
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HRH3 Q9Y5N1 1/20 0.35
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.34
S1PR1 P21453 2/20 0.34
FAAH O00519 1/20 0.34
MGLL Q99685 1/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.34
S1PR4 O95977 1/20 0.34
S1PR3 Q99500 1/20 0.34
S1PR5 Q9H228 1/20 0.34
VDR P11473 1/20 0.33
PLA2G4B P0C869 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27822526 1.00 ESR1 (0.39) ESR1NR5A1HDAC3HDAC1HDAC2
SCHEMBL11412994 1.00 ESR1 (0.39) ESR1NR5A1HDAC3HDAC1HDAC2
SCHEMBL1092732 0.93 ESR1 (0.36) ESR1HDAC3HDAC1HDAC2HRH3
SCHEMBL10745707 0.88 HRH3 (0.40) HRH3
SCHEMBL5145880 0.86 CNR2 (0.44) ESR1
SCHEMBL5145878 0.85 CYP3A4 (0.40) ESR1NR5A1HRH3TSHRTP53
SCHEMBL8469758 0.81 CNR2 (0.42) ESR1
SCHEMBL2783422 0.81 EPHX2 (0.35) ESR1TSHRKDM4EALDH1A1SMN1; SMN2
SCHEMBL5116391 0.81 HRH3 (0.41) HRH3MAPT
SCHEMBL21268265 0.79 PTGDR2 (0.38) ESR1FAAHMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1683782-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP claimed
EP-1683783-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP claimed
EP-1120402-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2008-06-25 EP claimed
CN-1310924-C Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2007-04-18 CN claimed
EP-1683782-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP claimed
EP-1683783-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP claimed
US-7009079-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US claimed
CN-1616465-A Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2005-05-18 CN claimed
US-20050090684-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO., LTD. 2005-04-28 US claimed
US-6670500-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-30 US claimed
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-10 US claimed
CN-1313277-A Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2001-09-19 CN claimed
EP-1120402-A2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP claimed
EP-0128012-B1 NOVEL CHIRAL COPPER COMPLEX AND ASYMMETRIC SYNTHESIS OF CYCLOPROPANECARBOXYLATE DERIVATIVES USING SAID COMPLEX AS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-20 EP claimed
US-4552972-A Chiral copper complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-12 US claimed
EP-0128012-A2 Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP claimed
US-4197408-A COPPER COMPLEX CATALYST, 2,5-DIMETHYL-2,4-HEXADIEN) REACTED WITH DIAZOACETATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-04-08 US claimed
US-4029690-A WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed
US-4029683-A WITH A SCHIFF BASE, CHRYSANTHEMATE SYNTHESIS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US claimed
CN-101528673-B Method for producing asymmetric copper complex crystal SUMITOMO CO LTD 2012-08-01 CN disclosed
US-8153830-B2 Production method of asymmetric copper complex crystal SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-10 US disclosed
EP-1683782-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
EP-1683783-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2012-03-14 EP disclosed
CN-101945590-A The deoxygenation mixture BASF SE 2011-01-12 CN disclosed
US-20100094036-A1 PRODUCTION METHOD OF ASYMMETRIC COPPER COMPLEX CRYSTAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-15 US disclosed
CN-101528673-A Method for producing asymmetric copper complex crystal SUMITOMO CHEMICAL CO (JP) 2009-09-09 CN disclosed
EP-2078710-A1 METHOD FOR PRODUCING ASYMMETRIC COPPER COMPLEX CRYSTAL Sumitomo Chemical Company, Limited (JP) 2009-07-15 EP disclosed
EP-1120402-B1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2008-06-25 EP disclosed
CN-1310924-C Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2007-04-18 CN disclosed
CN-1309723-C Method for producing optically active salicylaldimine copper complex SUMITOMO CHEMICAL CO (JP) 2007-04-11 CN disclosed
EP-1683782-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
EP-1683783-A2 Chiral copper complex and production processes thereof and using the same Sumitomo Chemical Company, Limited (JP) 2006-07-26 EP disclosed
CN-1246299-C Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2006-03-22 CN disclosed
US-7009079-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
CN-1616465-A Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO (JP) 2005-05-18 CN disclosed
US-20050090684-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL CO., LTD. 2005-04-28 US disclosed
US-6852871-B2 Method for producing optically active salicylaldimine copper complex SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2005-02-08 US disclosed
CN-1467211-A Method for producing optically active salicylaldimine copper complex ס�ѻ�ѧ��ҵ��ʽ���� 2004-01-14 CN disclosed
US-6670500-B2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-30 US disclosed
US-20030233003-A1 Method for producing optically active salicylaldimine copper complex SUMITOMO CHEMICAL COMPANY, LIMITED 2003-12-18 US disclosed
EP-1371631-A1 Method for producing optically active salicylaldimine copper complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-17 EP disclosed
US-6469198-B2 OBTAINED BY CONTACTING N-SALICYLIDENEAMINOALCOHOL WITH MONO OR DIVALENT COPPER COMPOUND; FORMATION OF OPTICALLY ACTIVE CYCLOPROPANE-CARBOXYLIC ESTER FROM PROCHIRAL OLEFIN AND DIAZOACETIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-10-22 US disclosed
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-10 US disclosed
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-11-01 US disclosed
CN-1313277-A Chiral copper complex, preparation method and application thereof SUMITOMO CHEMICAL CO (JP) 2001-09-19 CN disclosed
EP-1120401-A2 Chiral copper complex catalyst composition and asymmetric production process using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed
EP-1120402-A2 Chiral copper complex and production processes thereof and using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed
EP-0128012-B1 NOVEL CHIRAL COPPER COMPLEX AND ASYMMETRIC SYNTHESIS OF CYCLOPROPANECARBOXYLATE DERIVATIVES USING SAID COMPLEX AS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-11-20 EP disclosed
US-4603218-A Asymmetric synthesis of cyclopropanecarboxylate derivatives using chiral copper complex as catalyst SUMITOMO CHEMICAL CO., LTD. (JP) 1986-07-29 US disclosed
US-4552972-A Chiral copper complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-11-12 US disclosed
EP-0128012-A2 Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
EP-0022608-B1 PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACID ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-07-06 EP disclosed
US-4344894-A TRANSITION METAL COMPLEX OF SCHIFF BASES AS CATALYSTS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-08-17 US disclosed
US-4343935-A CATALYSTS FOR CYCLOPROPANIZATION OF OLEFINS BY DIAZOACETATES IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-08-10 US disclosed
US-4288387-A REACTION OF A HALOGENOPENTENE OR HEXENE WITH A DIAZOACETIC ESTER IN THE PRESENCE OF CATALYST WHICH IS METALLIC COPPER, A COPPER SALT, A RHODIUM SALT, OR A TRANSITION METAL COMPLEX OF A CHIRAL SCHIFF BASE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-09-08 US disclosed
EP-0024795-A1 Chiral compounds and process for their preparation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-03-11 EP disclosed
EP-0023075-A1 Process for the preparation of cyclopropane carboxylic acid esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-28 EP disclosed
EP-0022608-A1 Process for the preparation of cyclopropane carboxylic acid esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-01-21 EP disclosed
US-4197408-A COPPER COMPLEX CATALYST, 2,5-DIMETHYL-2,4-HEXADIEN) REACTED WITH DIAZOACETATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-04-08 US disclosed
US-4029690-A WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US disclosed
US-4029690-A WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US disclosed
US-4029683-A WITH A SCHIFF BASE, CHRYSANTHEMATE SYNTHESIS CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030233003-A1 Method for producing optically active salicylaldimine copper complex ADH1A, ALDH3A1, ADH1C ESR1 2927/4885NR5A1 553/4885HDAC3 4650/4885
US-20050090684-A1 Chiral copper complex and production processes thereof and using the same SOD1, CYP1A1, NFXL1 ESR1 633/4885NR5A1 831/4885HDAC3 4050/4885
US-20010037036-A1 Chiral copper complex catalyst composition and asymmetric production process using the same AP1M1, UBA3, AP1S1 ESR1 2902/4885NR5A1 847/4885HDAC3 4585/4885
US-20100094036-A1 PRODUCTION METHOD OF ASYMMETRIC COPPER COMPLEX CRYSTAL ADH1A, ADH1C, ALDH3A1 ESR1 3734/4885NR5A1 1429/4885HDAC3 4515/4885
US-20020004618-A1 Chiral copper complex and production processes thereof and using the same SOD1, XDH, NFXL1 ESR1 1529/4885NR5A1 448/4885HDAC3 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.