SCHEMBL29516443

SCHEMBL29516443

Nc1ccc2nc(-c3ccc(-c4nc5ccc(N)cc5o4)s3)oc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 12/20 0.65
▸ RAB9A P51151 12/20 0.65
▸ MAPT P10636 10/20 0.65
▸ SMN1; SMN2 Q16637 10/20 0.65
▸ KDM4E B2RXH2 8/20 0.65
▸ ALDH1A1 P00352 5/20 0.65
▸ HPGD P15428 4/20 0.65
▸ MEN1 O00255 4/20 0.65
▸ KMT2A Q03164 4/20 0.65
▸ GAA P10253 2/20 0.65
▸ GLA P06280 1/20 0.65
▸ TP53 P04637 8/20 0.51
▸ HSD17B10 Q99714 4/20 0.51
▸ GFER P55789 3/20 0.51
▸ F2RL3 Q96RI0 1/20 0.49
▸ RXFP1 Q9HBX9 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ PKM P14618 1/20 0.44
▸ PIK3CB P42338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12501435 0.81 KDM4E (0.78) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL2491134 0.80 RAB9A (0.96) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL12304277 0.79 HSD17B10 (0.63) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL2245075 0.79 RAB9A (1.00) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL12758426 0.78 KDM4E (0.49) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL28236480 0.77 RAB9A (0.67) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL28292707 0.77 RAB9A (0.96) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL16424489 0.76 NPC1 (0.75) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL517126 0.76 NPC1 (0.81) NPC1RAB9AMAPTSMN1; SMN2KDM4E
SCHEMBL30296291 0.76 NPC1 (0.75) NPC1RAB9AMAPTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264448-A Preparation method and application of coordination polymer-based electrocatalyst 大连理工大学 2025-01-07 — — CN claimed
CN-118599128-A Hydrogen bond organic framework material and preparation method and application thereof 浙江大学 2024-09-06 — — CN claimed
CN-118568850-A Dynamic pneumatic load distribution method and device based on generalized Chebyshev polynomial and electronic equipment 南京航空航天大学 2024-08-30 — — CN claimed
CN-114442483-A Self-adaptive non-periodic intermittent boundary control method 曲阜师范大学 2022-05-06 — — CN claimed
CN-111303439-B Preparation method of MOFs material and application of MOFs material in hydrogen isotope separation 中国工程物理研究院材料研究所 2022-03-29 — — CN claimed
CN-112537340-B Multi-train scattered event trigger control method based on discrete communication data 北京交通大学 2022-03-25 — — CN claimed
WO-2026102259-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM MOSAIC MATERIALS, INC. (US) 2026-05-15 — — WO disclosed
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM MOSAIC MAT INC (US) 2026-05-14 — — US disclosed
US-20260073949-A1 INTER-COVER PLACEMENT OF ENVIRONMENT-CONTROLLING SUBSTANCES IN DATA STORAGE DEVICES WESTERN DIGITAL TECHNOLOGIES, INC. (US) 2026-03-12 — — US disclosed
EP-4695023-A1 MODELING SELECTION OF POST COMBUSTION CARBON CAPTURE SORBENTS GE Vernova Technology GmbH (CH) 2026-02-18 — — EP disclosed
EP-4695731-A1 MACHINE LEARNING MODEL INCORPORATING PHYSICAL FEATURES OF SORBENTS FOR POST COMBUSTION CARBON CAPTURE GE Vernova Technology GmbH (CH) 2026-02-18 — — EP disclosed
US-20250388484-A1 UNCONVENTIONAL PHASE HEXAGONAL PRUSSIAN BLUE ANALOGS WITH OPEN STRUCTURES UNIV CITY HONG KONG (HK) 2025-12-25 — — US disclosed
CN-120904476-A Air-stable metal organic framework and preparation method and application thereof 中国工程物理研究院材料研究所 2025-11-07 — — CN disclosed
US-11517878-B2 Selective, adsorbate-induced spin state changes in transition metal-based metal-organic frameworks THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-06 — — US disclosed
US-11471494-B2 Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells SYNLOGIC OPERATING COMPANY, INC. (US) 2022-10-18 — — US disclosed
US-11332727-B2 Method for reducing an immune response by administering an immune evading adeno-associated AAV8 or AAVDJ viral vector THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-17 — — US disclosed
CN-114442483-A Self-adaptive non-periodic intermittent boundary control method 曲阜师范大学 2022-05-06 — — CN disclosed
EP-3988649-A1 METHODS, CELLS AND ORGANISMS Kymab Limited (GB) 2022-04-27 — — EP disclosed
CN-111303439-B Preparation method of MOFs material and application of MOFs material in hydrogen isotope separation 中国工程物理研究院材料研究所 2022-03-29 — — CN disclosed
CN-111303439-B Preparation method of MOFs material and application of MOFs material in hydrogen isotope separation 中国工程物理研究院材料研究所 2022-03-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260131275-A1 SYSTEM AND METHOD FOR TARGETED GAS DESORPTION FROM SORBENTS VIA AN EDUCTOR PUMP MECHANISM EXOSC9, EXOSC4, EXOSC5 NPC1 3311/4885RAB9A 397/4885MAPT 3402/4885
US-20250388484-A1 UNCONVENTIONAL PHASE HEXAGONAL PRUSSIAN BLUE ANALOGS WITH OPEN STRUCTURES HBG2, HBG1, HBB NPC1 1894/4885RAB9A 2148/4885MAPT 2396/4885
US-11517878-B2 Selective, adsorbate-induced spin state changes in transition metal-based metal-organic frameworks EPCAM, AP2S1, AP1S1 NPC1 2376/4885RAB9A 2665/4885MAPT 558/4885
US-20260073949-A1 INTER-COVER PLACEMENT OF ENVIRONMENT-CONTROLLING SUBSTANCES IN DATA STORAGE DEVICES TMCO1, VDAC1, VDAC2 NPC1 2357/4885RAB9A 1759/4885MAPT 459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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