Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.65 |
| ▸ | CES1 | P23141 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785837 | 0.83 | CES2 (0.54) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL3632219 | 0.81 | CES2 (0.67) | CES2CES1TSHRFAAHALDH1A1 | |
| SCHEMBL3293052 | 0.81 | CES1 (1.00) | CES2CES1TSHRAKR1B1PPARG | |
| SCHEMBL176299 | 0.80 | TSHR (0.50) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL3131865 | 0.78 | KMT2A (0.54) | CES2CES1TSHRFAAHPPARG | |
| SCHEMBL9539734 | 0.78 | TSHR (0.48) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL8668069 | 0.78 | KMT2A (0.54) | CES2CES1TSHRFAAHAKR1B1 | |
| Hydrogen Sulfide SCHEMBL9539728 | 0.78 | TSHR (0.48) | CES2CES1TSHRFAAHAKR1B1 | |
| SCHEMBL3632919 | 0.78 | KMT2A (0.54) | CES2CES1TSHRFAAHPPARG | |
| SCHEMBL11796286 | 0.78 | KMT2A (0.54) | CES2CES1TSHRFAAHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471802-A1 | Phosphoramidates of monosaccharides | Bioiberica, S.A. (ES) | 2012-07-04 | — | — | EP | claimed |
| US-6204302-B1 | INCLUDES (A) 1-ARYL-2-ALKYL-1,2-ETHANEDIONE AND (B) A RIGID 1,2-DIONE | BISCO, INC. | 2001-03-20 | — | — | US | claimed |
| EP-4056144-B1 | DENTAL ARTICLES, METHODS, AND KITS INCLUDING A COMPRESSIBLE MATERIAL | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-07-10 | — | — | EP | disclosed |
| US-12023392-B2 | Additive manufacturing process | DENTSPLY SIRONA INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-20240180791-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2024-06-06 | — | — | US | disclosed |
| EP-3265049-B1 | COMPOSITE MATERIAL HAVING CERAMIC FIBERS | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) | 2024-05-01 | — | — | EP | disclosed |
| CN-112673035-B | Composite material comprising ceramic fibers and nanoclusters, dental product, kit and method of making and using the same | 舒万诺知识产权公司 | 2024-04-19 | — | — | CN | disclosed |
| US-11931432-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-11925697-B2 | Dental impression material | DENTSPLY SIRONA INC. (US) | 2024-03-12 | — | — | US | disclosed |
| US-11918664-B2 | Direct dental filling compositions | DENTSPLY SIRONA INC. (US) | 2024-03-05 | — | — | US | disclosed |
| CN-113164328-B | Difunctional and multifunctional coinitiators in dental compositions | 登士柏德特里有限公司 | 2024-02-27 | — | — | CN | disclosed |
| US-20050176844-A1 | Self-etching emulsion dental compositions and methods | 3M DEUTSCHLAND GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
| US-20050175966-A1 | Self-adhesive dental compositions and methods | 3M DEUTSCHLAND GMBH (DE) | 2005-08-11 | — | — | US | disclosed |
| WO-2005034884-A1 | DENTAL COMPOSITIONS AND METHODS WITH ARYLSULFINATE SALTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |
| US-20050070627-A1 | Dental compositions and methods with arylsulfinate salts | 3M INNOVATIVE PROPERTIES COMPANY | 2005-03-31 | — | — | US | disclosed |
| WO-2005018581-A2 | SELF-ETCHING DENTAL COMPOSITIONS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20040206932-A1 | Compositions including polymerizable bisphosphonic acids and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-10-21 | — | — | US | disclosed |
| WO-2004060327-A1 | COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| US-6204302-B1 | INCLUDES (A) 1-ARYL-2-ALKYL-1,2-ETHANEDIONE AND (B) A RIGID 1,2-DIONE | BISCO, INC. | 2001-03-20 | — | — | US | disclosed |
| US-6204302-B1 | INCLUDES (A) 1-ARYL-2-ALKYL-1,2-ETHANEDIONE AND (B) A RIGID 1,2-DIONE | BISCO, INC. | 2001-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240180791-A1 | DENTAL COMPOSITION | CAD, MTR, ESD | CES2 1547/4885CES1 4418/4885TSHR 4609/4885 |
| US-11925697-B2 | Dental impression material | FHIT, PASK, TAS2R40 | CES2 944/4885CES1 3452/4885TSHR 2654/4885 |
| US-11931432-B2 | Dental composition | CAD, MTR, ESD | CES2 1547/4885CES1 4418/4885TSHR 4609/4885 |
| US-12023392-B2 | Additive manufacturing process | FLNA, FLNB, SAMM50 | CES2 4432/4885CES1 4588/4885TSHR 4003/4885 |
| US-11918664-B2 | Direct dental filling compositions | CAD, DOCK5, ITGA5 | CES2 3932/4885CES1 4480/4885TSHR 4680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.