Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29540788 | 0.99 | KIF11 (0.32) | ALDH1A1RAB9AHPGDKIF11MEN1 | |
| Hydrochloric Acid SCHEMBL29541614 | 0.97 | KIF11 (0.32) | KIF11MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL29541179 | 0.88 | ALDH1A1 (0.33) | ALDH1A1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL29635310 | 0.87 | ALDH1A1 (0.31) | ALDH1A1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL29635312 | 0.87 | ALDH1A1 (0.31) | ALDH1A1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL29540982 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL29635313 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL21797755 | 0.82 | L3MBTL1 (0.33) | ALDH1A1RAB9APLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL29540992 | 0.82 | L3MBTL1 (0.33) | ALDH1A1RAB9APLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL29540993 | 0.82 | L3MBTL1 (0.33) | ALDH1A1RAB9APLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234665-B | Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | claimed |
| EP-3555149-B1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS GMBH (AT) | 2025-11-12 | — | — | EP | disclosed |
| US-11639399-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2023-05-02 | — | — | US | disclosed |
| EP-3555148-B1 | CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2023-04-05 | — | — | EP | disclosed |
| US-11530280-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2022-12-20 | — | — | US | disclosed |
| US-20220325009-A1 | NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS | BOREALIS AG (AT) | 2022-10-13 | — | — | US | disclosed |
| CN-110337455-B | Catalyst system for the production of polyethylene copolymers in a high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-110234665-B | Catalyst system for preparing polyethylene copolymers in high temperature solution polymerization process | 博里利斯股份公司 | 2022-05-24 | — | — | CN | disclosed |
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | BOREALIS AG (AT) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279781-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | OPRM1, SIGMAR1, AP2S1 | ALDH1A1 4096/4885RAB9A 3854/4885HPGD 2972/4885 |
| US-11639399-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | C1S, SIGMAR1, C1R | ALDH1A1 4552/4885RAB9A 3725/4885HPGD 3940/4885 |
| US-11530280-B2 | Catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process | C1S, AP3S1, C5 | ALDH1A1 4551/4885RAB9A 3705/4885HPGD 3744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.