SCHEMBL29547423

SCHEMBL29547423

O=C(NC1CCCCC1)c1cc(-c2ccccc2)nc2ccc(Br)cc12

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.66
RXFP1 Q9HBX9 3/20 0.62
ALDH1A1 P00352 5/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
LMNA P02545 3/20 0.59
KDM4E B2RXH2 2/20 0.59
GAA P10253 3/20 0.56
KLK7 P49862 1/20 0.55
MAPT P10636 3/20 0.55
P4HB P07237 1/20 0.55
MEN1 O00255 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
RAB9A P51151 1/20 0.54
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29578969 0.94 KMT2A (0.73) KMT2ARXFP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL14970878 0.87 KDM4E (0.75) KMT2ARXFP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL14132431 0.80 MAPT (0.81) KMT2ARXFP1ALDH1A1LMNAKDM4E
SCHEMBL1899098 0.78 RXFP1 (0.79) KMT2ARXFP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL12237494 0.76 RXFP1 (0.75) KMT2ARXFP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL1901514 0.75 PLA2G2A (0.73) KMT2ARXFP1ALDH1A1LMNAKDM4E
SCHEMBL21836072 0.74 ALDH1A1 (0.72) KMT2AALDH1A1SMN1; SMN2KDM4EGAA
SCHEMBL21993198 0.74 ALDH1A1 (0.72) KMT2AALDH1A1SMN1; SMN2KDM4EGAA
SCHEMBL12218347 0.74 RAB9A (0.92) KMT2AALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL23722851 0.73 KDM4E (0.67) KMT2AALDH1A1SMN1; SMN2LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117761915-A Anti-aging resin lens and preparation method thereof 江苏万新光学有限公司 2024-03-26 CN claimed
US-12558205-B2 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby ODS CO., LTD. (KR) 2026-02-24 US disclosed
CN-119735791-A Magnetic nano-particle and preparation method and application thereof 首都医科大学 2025-04-01 CN disclosed
CN-112099720-B Digital assistant user interface and response mode 苹果公司 2025-03-18 CN disclosed
CN-114729178-B Polycarbonate diol composition and coating composition using same 旭化成株式会社 2025-03-18 CN disclosed
CN-118984810-A Method for preparing calcium carbonate from calcium-containing medium 生态之星诺泰克有限责任公司 2024-11-19 CN disclosed
CN-117761915-A Anti-aging resin lens and preparation method thereof 江苏万新光学有限公司 2024-03-26 CN disclosed
CN-117186464-A Polyaryl hexahydropyrimidine type anion exchange membrane and preparation method thereof 黑龙江大学 2023-12-08 CN disclosed
CN-117164913-A Cross-linked polyarylpiperidine anion exchange membrane and preparation method thereof 北京志氢科技有限公司 2023-12-05 CN disclosed
US-11834404-B2 Derivatives of sulindac can protect normal cells against oxidative damage UNIVERSITY OF SOUTH ALABAMA (US) 2023-12-05 US disclosed
US-20230293276-A1 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby ODS CO., LTD. (KR) 2023-09-21 US disclosed
US-20230241373-A1 WEARABLE CARDIAC THERAPEUTIC DEVICES WITH HYDROPHOBIS AND/OR HYDROPHILIC DIELECTRIC FIBERS ZOLL MEDICAL CORPORATION 2023-08-03 US disclosed
CN-114591506-B Modified diene rubber and preparation method thereof 中国石油化工股份有限公司 2023-07-21 CN disclosed
CN-115853064-A Cooling tower exhaust recovery water intake system based on lithium bromide unit drive 哈尔滨商业大学 2023-03-28 CN disclosed
US-20230023221-A1 POLYCARBONATE DIOL COMPOSITION AND COATING MATERIAL COMPOSITION COMPRISING SAME ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-26 US disclosed
EP-4059993-A1 POLYCARBONATE DIOL COMPOSITION AND COATING COMPOSITION IN WHICH SAME IS USED Asahi Kasei Kabushiki Kaisha (JP) 2022-09-21 EP disclosed
CN-114729178-A Polycarbonate diol composition and coating composition using same 旭化成株式会社 2022-07-08 CN disclosed
CN-114591506-A Modified diene rubber and preparation method thereof 中国石油化工股份有限公司 2022-06-07 CN disclosed
CN-114524912-A Side-chain piperidine cation grafted polybiphenyl alkaline membrane and preparation method thereof 北京化工大学 2022-05-24 CN disclosed
US-20220106250-A1 DERIVATIVES OF SULINDAC CAN PROTECT NORMAL CELLS AGAINST OXIDATIVE DAMAGE UNIVERSITY OF SOUTH ALABAMA (US) 2022-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834404-B2 Derivatives of sulindac can protect normal cells against oxidative damage PRDX3, PRDX5, SQOR KMT2A 4332/4885RXFP1 3821/4885ALDH1A1 425/4885
US-20230293276-A1 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby PHOSPHO1, ALPG, COX6B1 KMT2A 1143/4885RXFP1 4420/4885ALDH1A1 2773/4885
US-12558205-B2 Composition for forming artificial tooth, method of preparing artificial tooth, and artificial tooth prepared thereby PFN1, GPX1, TFAM KMT2A 706/4885RXFP1 3477/4885ALDH1A1 3207/4885
US-20220106250-A1 DERIVATIVES OF SULINDAC CAN PROTECT NORMAL CELLS AGAINST OXIDATIVE DAMAGE PRDX3, PRDX5, SQOR KMT2A 4332/4885RXFP1 3821/4885ALDH1A1 425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.