Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698216 | 0.84 | HDAC1 (0.40) | KDM4EGAACYP2D6CYP3A4 | |
| SCHEMBL1698200 | 0.82 | KDM4E (0.39) | HTR2AHTR2CHTR2BHRH3KDM4E | |
| SCHEMBL12379331 | 0.77 | IDH1 (0.33) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL3835964 | 0.72 | OPRL1 (0.36) | OPRL1 | |
| SCHEMBL25967564 | 0.70 | NOS1 (0.37) | KDM4EGAAOPRL1 | |
| SCHEMBL461946 | 0.69 | HTR2A (0.54) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL7545824 | 0.68 | HTR2A (0.53) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL29949831 | 0.67 | PLAU (0.44) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL14990041 | 0.67 | PLAU (0.44) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL9742041 | 0.67 | CHRNA7 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391790-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | TARO PHARMACEUTICALS INC. (CA) | 2023-12-07 | — | — | US | disclosed |
| US-11773108-B2 | Indene derivatives useful in treating pain and inflammation | TARO PHARMACEUTICALS INC. (CA) | 2023-10-03 | — | — | US | disclosed |
| US-11352367-B2 | Indene derivatives useful in treating pain and inflammation | TARO PHARMACEUTICALS INC. (CA) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391790-A1 | INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION | IL1B, IL1A, LTB4R | HTR2A 782/4885HTR2C 978/4885HTR2B 276/4885 |
| US-11352367-B2 | Indene derivatives useful in treating pain and inflammation | IL1B, IL1A, LTB4R | HTR2A 782/4885HTR2C 978/4885HTR2B 276/4885 |
| US-11773108-B2 | Indene derivatives useful in treating pain and inflammation | IL1B, IL1A, LTB4R | HTR2A 773/4885HTR2C 962/4885HTR2B 286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.