Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20051812 | 1.00 | XDH (0.52) | XDHADORA2AADORA1IDO1NOTUM | |
| SCHEMBL29045675 | 0.80 | LTA4H (0.51) | ADORA2ANOTUMKDM1A | |
| SCHEMBL14564374 | 0.77 | ENPP3 (0.45) | ADORA2AADORA1 | |
| SCHEMBL14065409 | 0.76 | CA1 (0.40) | XDHADORA2AADORA1 | |
| SCHEMBL901316 | 0.76 | ASIC3 (0.56) | XDHADORA2AADORA1IDO1ATR | |
| SCHEMBL4539598 | 0.76 | RAB9A (0.54) | ADORA2AADORA1IDO1GRM5 | |
| SCHEMBL8119166 | 0.74 | LTA4H (0.54) | ADORA2AADORA1NOTUM | |
| SCHEMBL29615077 | 0.73 | GRM5 (0.50) | XDHADORA2AADORA1IDO1NOTUM | |
| SCHEMBL19471325 | 0.73 | XDH (0.65) | XDHADORA2AADORA1IDO1ATR | |
| SCHEMBL30552612 | 0.73 | ALDH1A1 (0.59) | XDHADORA2AADORA1IDO1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803963-B | Cyano-substituted heterocycles having USP30 inhibitor activity | 特殊治疗有限公司 | 2022-04-26 | — | — | CN | disclosed |