Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL18670526 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL5550827 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL59778 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL4418857 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL715749 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL184653 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL38658647 | 0.96 | LMNA (0.35) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL5884527 | 0.92 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL17007806 | 0.92 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA | |
| Pyrophosphoric Acid SCHEMBL11779407 | 0.92 | CA1 (0.33) | CA1CA4CA5ACA5BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022092135-A1 | METHOD FOR IMPROVING ADHESIVE STRENGTH OF ADHESIVE AGENT OF RESIN MOLDED ARTICLE, AND COMPOSITE HAVING IMPROVED ADHESIVE STRENGTH | ＥＮＥＯＳ株式会社 | 2022-05-05 | — | — | WO | disclosed |