SCHEMBL29618947

SCHEMBL29618947

O=C1CC(C(=O)OCC2c3ccccc3-c3ccccc32)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.48
FABP7 O15540 2/20 0.48
TSHR P16473 1/20 0.44
KMT2A Q03164 2/20 0.43
ALDH1A1 P00352 1/20 0.43
EPHX2 P34913 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
IDO1 P14902 1/20 0.36
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2367056 1.00 FABP5 (0.48) FABP5FABP7TSHRKMT2AALDH1A1
SCHEMBL31532292 1.00 FABP5 (0.48) FABP5FABP7TSHRKMT2AALDH1A1
SCHEMBL29883515 0.80 TSHR (0.42) FABP5FABP7TSHRKMT2AALDH1A1
SCHEMBL3515128 0.80 TSHR (0.42) FABP5FABP7TSHRKMT2AALDH1A1
SCHEMBL4611910 0.79 KMT2A (0.49) TSHRKMT2AEPHX2
SCHEMBL2774790 0.76 FABP5 (0.48) FABP5FABP7TSHRKMT2AEPHX2
SCHEMBL789074 0.76 FABP5 (0.48) FABP5FABP7TSHRKMT2AEPHX2
SCHEMBL29430507 0.76 FABP5 (0.48) FABP5FABP7TSHRKMT2AEPHX2
SCHEMBL5227458 0.75 GPBAR1 (0.51) FABP5FABP7TSHRRAB9ASMN1; SMN2
SCHEMBL274968 0.75 GPBAR1 (0.51) FABP5FABP7TSHRRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025160177-A9 COMPOSITIONS AND METHODS FOR ORGAN AND CELL TARGETED DELIVERY THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-10-30 WO disclosed
EP-4596566-A1 COMPOUND PRODUCTION METHOD The University of Tokyo (JP) 2025-08-06 EP disclosed
CN-119968380-A Process for producing compound 国立大学法人东京大学 2025-05-09 CN disclosed
US-20240190924-A1 Synthesis of Gamma Peptide Nucleic Acid Monomers and Oligomers, and Applications Therefor CARNEGIE MELLON UNIVERSITY 2024-06-13 US disclosed
US-11970512-B2 Amphotericin B derivatives with improved therapeutic index THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-04-30 US disclosed
WO-2024071320-A1 COMPOUND PRODUCTION METHOD 国立大学法人東京大学 2024-04-04 WO disclosed
EP-3596089-B1 ANTIBACTERIAL COMPOUNDS UNIV NOTTINGHAM (GB) 2023-12-06 EP disclosed
CN-110407898-B Amphotericin B derivatives with improved therapeutic index 伊利诺伊大学评议会 2023-12-01 CN disclosed
US-20230097883-A1 ERGOTHIONEINE PET COMPOUNDS AND METHODS OF USE THEREOF VANDERBILT UNIVERSITY 2023-03-30 US disclosed
US-20230082311-A1 DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) 2023-03-16 US disclosed
US-20230016424-A1 HYBRID AMIDE DERIVATIVES OF AMPHOTERICIN B THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2023-01-19 US disclosed
US-20230000891-A1 HYBRID AMPHOTERICIN B DERIVATIVES WITH REDUCED TOXICITY THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2023-01-05 US disclosed
US-11447524-B2 Multifunction cyclic peptide polymer nanomaterials THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2022-09-20 US disclosed
WO-2022187216-A1 SYNTHESIS OF GAMMA PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS, AND APPLICATIONS THEREFOR CARNEGIE MELLON UNIVERSITY (US) 2022-09-09 WO disclosed
EP-3261639-B1 SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS VERSEON INT CORPORATION (US) 2022-08-24 EP disclosed
EP-4029514-A1 DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME National University Corporation Kumamoto University (JP) 2022-07-20 EP disclosed
CN-114761033-A Medicament for radical therapy of refractory hereditary nephrotic Alport syndrome 国立大学法人熊本大学 2022-07-15 CN disclosed
CN-114555094-A Mixed amide derivatives of amphotericin B 伊利诺伊大学评议会 2022-05-27 CN disclosed
CN-114502173-A Mixed amphotericin B derivatives with reduced toxicity 伊利诺伊大学评议会 2022-05-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230016424-A1 HYBRID AMIDE DERIVATIVES OF AMPHOTERICIN B AADAC, NAAA, NAT10 FABP5 4064/4885FABP7 2100/4885TSHR 3576/4885
US-20240190924-A1 Synthesis of Gamma Peptide Nucleic Acid Monomers and Oligomers, and Applications Therefor POLL, PCNA, POLQ FABP5 2441/4885FABP7 566/4885TSHR 3133/4885
US-20230097883-A1 ERGOTHIONEINE PET COMPOUNDS AND METHODS OF USE THEREOF GPX1, TSPO, GSTO1 FABP5 871/4885FABP7 104/4885TSHR 2682/4885
US-20230000891-A1 HYBRID AMPHOTERICIN B DERIVATIVES WITH REDUCED TOXICITY ERG28, PAICS, CERT1 FABP5 4337/4885FABP7 2352/4885TSHR 3983/4885
US-20230082311-A1 DRUG FOR CURATIVE THERAPY OF INTRACTABLE HEREDITARY RENAL ALPORT SYNDROME FKBP3, FKBP4, ATG4A FABP5 1943/4885FABP7 3437/4885TSHR 4873/4885
US-11447524-B2 Multifunction cyclic peptide polymer nanomaterials NGLY1, PTMS, PNISR FABP5 4618/4885FABP7 3893/4885TSHR 1236/4885
US-11970512-B2 Amphotericin B derivatives with improved therapeutic index C9, AMPD3, C5 FABP5 1398/4885FABP7 2223/4885TSHR 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.