Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19725740 | 0.88 | TSHR (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL2280203 | 0.88 | TSHR (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL3438664 | 0.88 | TSHR (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL5075106 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL22809 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL1282784 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL8061841 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL11041621 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL219917 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD | |
| SCHEMBL283124 | 0.88 | NAAA (0.50) | TSHRNAAARECQLMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260117035-A1 | VISCOELASTIC POLYURETHANE FOAM WITH COATING | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-04-30 | — | — | US | disclosed |
| US-12577360-B2 | Viscoelastic polyurethane foam with coating | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-12012521-B2 | Polymer mixture, multilayer article containing the same, and process of preparing the multilayer article | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-06-18 | — | — | US | disclosed |
| CN-114981351-B | Polymer mixture, multilayer article comprising the same and process for preparing the multilayer article | 陶氏环球技术有限责任公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117624426-A | Transparent ABS graft stabilizer and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20240043644-A1 | Viscoelastic Polyurethane Foam with Coating | ROHM AND HAAS COMPANY | 2024-02-08 | — | — | US | disclosed |
| EP-3797137-B1 | ALL TEMPERATURE WATER BORNE SEALANT | RED DEVIL INC (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3328908-B1 | OLIGOMER SEED FOR SYNTHESIS OF UNIMODAL ACRYLIC BEAD PARTICLES | ROHM & HAAS (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116925291-A | Oligomer seed crystals for the synthesis of unimodal acrylic beads | 罗门哈斯公司 | 2023-10-24 | — | — | CN | disclosed |
| US-11718697-B2 | Multi-stage latex particles with peg in outer stage | COLUMBIA INSURANCE COMPANY (US) | 2023-08-08 | — | — | US | disclosed |
| CN-112689465-B | Coated open cell polyurethane foam structure with heat absorbing capability | 陶氏环球技术有限责任公司 | 2023-05-26 | — | — | CN | disclosed |
| EP-4144416-A1 | FOAMING SUNSCREEN COMPOSITION CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING COMPOUND AND A SUPERHYDROPHILIC AMPHIPHILIC COPOLYMER | Johnson & Johnson Consumer Inc. (US) | 2023-03-08 | — | — | EP | disclosed |
| US-20220403085-A1 | MULTI-STAGE LATEX PARTICLES WITH PEG IN OUTER STAGE | COLUMBIA INSURANCE CO (US) | 2022-12-22 | — | — | US | disclosed |
| US-20220389234-A1 | POLYMER MIXTURE, MULTILAYER ARTICLE CONTAINING THE SAME, AND PROCESS OF PREPARING THE MULTILAYER ARTICLE. | DOW GLOBAL TECHNOLOGIES LLC | 2022-12-08 | — | — | US | disclosed |
| EP-4093818-A1 | POLYMER MIXTURE, MULTILAYER ARTICLE CONTAINING THE SAME, AND PROCESS OF PREPARING THE MULTILAYER ARTICLE | Dow Global Technologies LLC (US) | 2022-11-30 | — | — | EP | disclosed |
| EP-3840612-B1 | COATED OPEN-CELL POLYURETHANE FOAM STRUCTURES WITH THERMAL ABSORPTION CAPABILITIES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-09-21 | — | — | EP | disclosed |
| US-11447591-B2 | Multi-stage latex particles with peg in outer stage | COLUMBIA INSURANCE COMPANY (US) | 2022-09-20 | — | — | US | disclosed |
| CN-114981351-A | Polymer mixture, multilayer article comprising the same and process for preparing the multilayer article | 陶氏环球技术有限责任公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-109219625-B | Viscoelastic polyurethane foam with coating | 陶氏环球技术有限责任公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-3349723-B1 | SUNSCREEN COMPOSITIONS COMPRISING SUPERHYDROPHILIC AMPHIPHILIC COPOLYMERS | JOHNSON & JOHNSON CONSUMER INC (US) | 2022-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117035-A1 | VISCOELASTIC POLYURETHANE FOAM WITH COATING | RAD54L, TPD52L2, XRCC6 | TSHR 4513/4885NAAA 2350/4885RECQL 1029/4885 |
| US-12577360-B2 | Viscoelastic polyurethane foam with coating | RAD54L, XRCC6, MCM7 | TSHR 4032/4885NAAA 1757/4885RECQL 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.